MLLT1 Antibody - BSA Free

Immunoprecipitation: MLLT1 Antibody [NBP1-26652] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit used for IP at 3 mcg/mg lysate. MLLT1 was also immunoprecipitated by rabbit anti- MLLT1 antibody NBP1-26653, which recognizes a downstream epitope

• Reactivity: Hu
• Applications: IP, WB (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

MLLT1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit MLLT1 Antibody - BSA Free (NBP1-26652) is a polyclonal antibody validated for use in IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 150 and 200 of human myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 using the numbering given in entry NP_005925.2 (GeneID 4298).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MLLT1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 3-5 ug/mg lysate
• Application Notes: It is not recommended for western analysis.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for MLLT1 Antibody - BSA Free

• ENLENL/MLL fusion
• LTG19MLLT1/MLL fusion
• myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog);translocated to, 1
• myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 1
• protein ENL
• YEATS domain-containing protein 1
• YEATS1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocatedto, 1

Background

MLLT1, also known as ENL (eleven nineteen leukemia protein), was originally identified as a gene involved in a recurrent translocation (11;19) with the mixed-lineage leukemia (MLL) gene. The MLL-ENL fusion protein has been found to associate with SWI/SNF complexes and promote transcription from the HoxA7 promoter. Additionally, from studies to identify proteins that associate with MLLT1, MLLT1 is suggested to play a role in histone modification and transcriptional elongation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MLLT1
• Entrez:
  • 4298(Human)
• Uniprot:
  • NP_005925.2(Human)