MLLT1 Products

Description

MLLT1, also known as ENL (eleven nineteen leukemia protein), was originally identified as a gene involved in a recurrent translocation (11;19) with the mixed-lineage leukemia (MLL) gene. The MLL-ENL fusion protein has been found to associate with SWI/SNF complexes and promote transcription from the HoxA7 promoter. Additionally, from studies to identify proteins that associate with MLLT1, MLLT1 is suggested to play a role in histone modification and transcriptional elongation.

Bioinformatics

Entrez	4298 Human
Uniprot	Q03111 Human AAI48807.1 Human NP_005925 Human NP_005925.2 Human
Product By Gene ID	4298
Alternate Names	protein ENL YEATS domain-containing protein 1 YEATS1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocatedto, 1 LTG19MLLT1/MLL fusion ENLENL/MLL fusion myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog);translocated to, 1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 1

Diseases related to MLLT1

Discover more about diseases related to MLLT1.

Leukemia
Chromosomal Translocation
Myeloid Leukemia
Acute Leukemia
Leukemia, Myelocytic, Acute
Acute Lymphocytic Leukemia
Leukemogenesis
Malignant Neoplasms
Cell Transformation, Neoplastic
Precursor T-cell Lymphoblastic Leukemia-lymphoma
Precursor B-cell Lymphoblastic Leukemia-lymphoma
Cytogenetic Abnormality
Neoplasm, Residual
Chromosome Breakage
Secondary Acute Myeloid Leukemia
Adult T-cell Lymphoma/leukemia
Acute Monocytic Leukemia

Pathways for MLLT1

View related products by pathway and learn more about each of the pathways below.

Cell Development
Cell Adhesion
Induction Of Apoptosis
Cellular Senescence
Synaptic Transmission
Histone Modification
Localization
Cell Cycle Arrest
Senescence
Mismatch Repair
Cell Cycle
Tissue Remodeling
Fibrinolysis
Dna Modification
Interphase
Chromatin Modification
Pathogenesis

PTMs for MLLT1

Learn more about PTMs related to MLLT1.

Methylation

Bioinformatics Tool for MLLT1

Discover related pathways, diseases and genes to MLLT1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.