Lymphotoxin beta R/TNFRSF3 Antibody (3C8) [Biotin] Summary
The immunogen for this antibody was Lymphotoxinbeta Receptor.
Protein A or G purified
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Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Biotin (A=N/A, E=N/A)
Aqueous buffer, may contain carrier protein/stabilizer (proprietary)
0.09% Sodium Azide
Protein A or G purified
- Flow Cytometry 1:10-1:1000
This 3C8 antibody has been tested by flow cytometric analysis of NIH/3T3 cells. This can be used at less than or equal to 0.5 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test. It is recommended to block Fcgamma-receptors with anti-mouse CD16/32, prior to staining to prevent non-specific binding of 3C8. Furthermore,
Alternate Names for Lymphotoxin beta R/TNFRSF3 Antibody (3C8) [Biotin]
- lymphotoxin B receptor
- lymphotoxin beta receptor (TNFR superfamily, member 3)
- Lymphotoxin-beta receptor
- TNF RIII
- TNF Rrp
- TNFR superfamily, member 3
- Tumor necrosis factor C receptor
- Tumor necrosis factor receptor 2-related protein
- tumor necrosis factor receptor superfamily member 3
- tumor necrosis factor receptor superfamily, member 3
- Tumor necrosis factor receptor type III
The antibody reacts with mouse lymphotoxin-beta receptor (LTBR). Northern blot analysis of tissues from adult mice showed that expression levels of LTBR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. The tumor necrosis factor receptor-related protein is the human receptor for the heterotrimer of lymphotoxin-alpha and lymphotoxin-beta. This LT-alpha/LT-beta heterotrimer (LT-alpha1beta2) is assumed to take part in immunologic reactions by cell-cell contact, but does not bind to either TNFR1 (CD120alpha) or TNFR2 (CD120beta). LTBR is expressed by day 7 embryos, so it has been speculated that the LT-alpha/LT-beta receptor system may also have some function in early embryogenesis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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