Lymphotoxin-alpha/TNF-beta Antibody - BSA Free

Western Blot: Lymphotoxin-alpha/TNF-beta Antibody [NBP1-87725] - Analysis in control (vector only transfected HEK293T lysate) and lTA over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Immunohistochemistry-Paraffin: Lymphotoxin-alpha/TNF-beta Antibody [NBP1-87725] - Staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Lymphotoxin-alpha/TNF-beta Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Lymphotoxin-alpha/TNF-beta Antibody - BSA Free (NBP1-87725) is a polyclonal antibody validated for use in IHC and WB. Anti-Lymphotoxin-alpha/TNF-beta Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: HSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LTA
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: IHC reported in scientific literature (PMID: 24566624). HIER pH6 retrieval is recommended.
• Control Peptide:

  Lymphotoxin-alpha/TNF-beta Protein (NBP1-87725PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Lymphotoxin-alpha/TNF-beta Antibody - BSA Free

• LT
• LTA
• LT-alpha
• lymphotoxin alpha (TNF superfamily, member 1)
• Lymphotoxin alpha
• Lymphotoxinalpha
• Lymphotoxin-alpha
• tnfb
• TNF-beta
• TNFBlymphotoxin-alpha
• TNFSF1
• TNFSF1B
• TNFSF1TNF-beta
• tumor necrosis factor beta
• Tumor necrosis factor ligand superfamily member 1

Background

TNF-beta (tumor necrosis factor beta, lymphotoxin alpha, TNFSF1, TNF ligand superfamily member 1) a member of the TNF ligand superfamily and a potent lymphoid factor, is mainly produced by activated T and B lymphocytes and leukocytes. TNF-beta is also produced by fibroblasts, astrocytes, myeloma cells, endothelial cells and epithelial cells. TNF-beta mediates inflammatory and immune responses, has cytotoxic activity on tumor cells and other target cells and shares many of the same bioactivities as TNF alpha, including regulation of cell proliferation, differentiation and apoptosis. TNF-beta is not species-specific and human TNF-beta is active on murine cells with a slightly reduced specific activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Lymphotoxin-alpha/TNF-beta Antibody (NBP1-87725)(1)

Publication using NBP1-87725

• Kallio KA, Marchesani M, Vlachopoulou E et al. Genetic Variation on the BAT1-NFKBIL1-LTA Region of Major Histocompatibility Complex Class III Associates with Periodontitis. Infect Immun 2014-05-01 [PMID: 24566624] (IF/IHC, Human)

Bioinformatics

• Gene Symbol: LTA