LITAF Antibody

Images

 
Western Blot: LITAF Antibody [NBP1-32726] - (30 ug of whole cell lysate) A: Hep G2 12% SDS PAGE diluted at 1:1000
Immunohistochemistry-Paraffin: LITAF Antibody [NBP1-32726] - Paraffin-embedded placenta. LITAF antibody [N1C3] dilution: 1:100.

Product Details

Summary
Reactivity Hu, MkSpecies Glossary
Applications WB, ChIP, IHC, IHC-P, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

LITAF Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human LITAF. The exact sequence is proprietary.
Localization
Lysosome membrane, Peripheral membrane protein, Cytoplasmic side
Predicted Species
Monkey (96%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LITAF
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Chromatin Immunoprecipitation 1:10 - 1:500
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Immunoprecipitation
Theoretical MW
17 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Rhesus Monkey (96%), Mouse (85%), Rat (86%), Bovine (86%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for LITAF Antibody

  • CMT1C
  • FLJ38636
  • lipopolysaccharide-induced TNF factor
  • lipopolysaccharide-induced TNF-alpha factor
  • lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • LITAF
  • LPS-induced TNF-alpha factor
  • MGC116698
  • MGC116700
  • MGC125275
  • MGC125276
  • p53-induced gene 7 protein
  • PIG7
  • PIG7MGC116701
  • SIMPLE
  • SIMPLEMGC125274
  • Small integral membrane protein of lysosome/late endosome
  • TP53I7
  • tumor protein p53 inducible protein 7

Background

Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ChIP Video Protocol
ChIP Webinar

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol LITAF
Entrez