LITAF Antibody - BSA Free

Western Blot: LITAF Antibody [NBP1-32726] - (30 ug of whole cell lysate) A: Hep G2 12% SDS PAGE diluted at 1:1000

Immunohistochemistry-Paraffin: LITAF Antibody [NBP1-32726] - Paraffin-embedded placenta. LITAF antibody [N1C3] dilution: 1:100.

• Reactivity: Hu, Pm
• Applications: WB, IHC, IP, ChIP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

LITAF Antibody - BSA Free Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human LITAF. The exact sequence is proprietary.
• Localization: Lysosome membrane, Peripheral membrane protein, Cytoplasmic side
• Predicted Species: Monkey (96%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LITAF
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Chromatin Immunoprecipitation (ChIP) 1:10-1:500
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Immunoprecipitation
  • Western Blot 1:500-1:3000
• Theoretical MW: 17 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Rhesus Monkey (96%), Mouse (85%), Rat (86%), Bovine (86%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for LITAF Antibody - BSA Free

• CMT1C
• FLJ38636
• lipopolysaccharide-induced TNF factor
• lipopolysaccharide-induced TNF-alpha factor
• lipopolysaccharide-induced tumor necrosis factor-alpha factor
• LITAF
• LPS-induced TNF-alpha factor
• MGC116698
• MGC116700
• MGC125275
• MGC125276
• p53-induced gene 7 protein
• PIG7
• PIG7MGC116701
• SIMPLE
• SIMPLEMGC125274
• Small integral membrane protein of lysosome/late endosome
• TP53I7
• tumor protein p53 inducible protein 7

Background

Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: LITAF