LIGHT/TNFSF14 Antibody (MM0456-8C34) - Azide and BSA Free

Western Blot: LIGHT/TNFSF14 Antibody (MM0456-8C34) [NBP2-11964] - Lysates of HEK293 expressing human LIGHT/TNFSF14.

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: MM0456-8C34
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

LIGHT/TNFSF14 Antibody (MM0456-8C34) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse LIGHT/TNFSF14 Antibody (MM0456-8C34) - Azide and BSA Free (NBP2-11964) is a monoclonal antibody validated for use in Flow. Anti-LIGHT/TNFSF14 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Human recombinant LIGHT/TNFSF14 (extracellular domain)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TNFSF14
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 1:10-1:1000
• Application Notes: This antibody is Cytof ready.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for LIGHT/TNFSF14 Antibody (MM0456-8C34) - Azide and BSA Free

• CD258 antigen
• CD258
• delta transmembrane LIGHT
• Herpes virus entry mediator ligand
• Herpesvirus entry mediator ligand
• HVEM-L
• HVEMLherpesvirus entry mediator-ligand
• ligand for herpesvirus entry mediator
• LIGHT
• LIGHTherpesvirus entry mediator A
• LTg
• TNFSF14
• TR2
• tumor necrosis factor (ligand) superfamily, member 14
• tumor necrosis factor ligand superfamily member 14
• tumor necrosis factor receptor-like 2
• tumor necrosis factor superfamily member LIGHT

Background

TNFSF14 is encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for LIGHT/TNFSF14 Antibody (NBP2-11964)(1)

Publication using NBP2-11964

• Ventura A, Vassall A, Robinson E et al. Extracorporeal Photochemotherapy Drives Monocyte-to-Dendritic Cell Maturation to Induce Anti-Cancer Immunity Cancer Res. 2018-05-15 [PMID: 29764863] (FLOW)

Bioinformatics

• Gene Symbol: TNFSF14
• Uniprot:
  • O43557()