Lgr5/GPR49 Antibody [DyLight 650]


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Product Details

Reactivity HuSpecies Glossary
Applications IHC, IHC-P
DyLight 650

Lgr5/GPR49 Antibody [DyLight 650] Summary

Synthetic peptide [KLH conjugated] made to the 2nd cytoplasmic loop of human GPR49/LGR5. [UniProt# O75473]
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunohistochemistry 5-8 ug/ml
  • Immunohistochemistry-Paraffin 5-8 ug/ml
Application Notes
This antibody may be used for immunohistochemistry on paraffin sections.

Reactivity Notes

Human. Immunogen sequence has 81% identity with mouse.

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Immunogen affinity purified


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Lgr5/GPR49 Antibody [DyLight 650]

  • FEX
  • G protein-coupled receptor 49
  • GPR49
  • GPR49G-protein coupled receptor HG38
  • GPR67
  • G-protein coupled receptor 49
  • G-protein coupled receptor 67
  • GRP49
  • HG38
  • leucine-rich repeat containing G protein-coupled receptor 5
  • leucine-rich repeat-containing G protein-coupled receptor 5
  • leucine-rich repeat-containing G-protein coupled receptor 5
  • Lgr5
  • MGC117008
  • orphan G protein-coupled receptor HG38


GPR49 is an Orphan-A GPCR with an unknown ligand. G protein-coupled receptor GPR49 has been reported to be expressed in brain, skeletal muscle, placenta, and spinal cord. ESTs have been isolated from normal human brain (amygdala), embryo, and placenta libraries and from human germ cell, uterus, and brain (neuroblastoma) cancer libraries.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for Lgr5/GPR49 Antibody (NLS1235C). (Showing 1 - 1 of 1 FAQ).

  1. Can you confirm whether or not NLS1235C is supported for use in ICC application? Has it been tested in ICC and shown to be ineffective?
    • Unfortunately, neither the base antibody NLS1235 nor NLS1235C has been tested in ICC/IF. Therefore we don't know whether it will work in ICC. This series of the anybodies with the conjugation formats have only been validated in IHC-P with the human specimens. If you would like to test an antibody in an untested species and/or application and share your results with us, I can recommend our Innovator's Reward program. Our Innovator's Reward program was created to allow researchers the opportunity to try our primary antibodies in an untested species or application, without the financial risk of failure. To participate you simply submit an online review detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Reviews may also be submitted by emailing Innovators Reward.

Secondary Antibodies


Isotype Controls

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Gene Symbol LGR5