LASS6 Antibody

Images

 
Western Blot: LASS6 Antibody [NBP1-76965] - Rat brain tissue lysate with LASS6 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: LASS6 Antibody [NBP1-76965] - Immunofluorescence of LASS6 in Mouse Brain cells with LASS6 antibody at 5 ug/mL.
Immunohistochemistry-Paraffin: LASS6 Antibody [NBP1-76965] - Mouse brain tissue with LASS6 antibody at 2.5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

LASS6 Antibody Summary

Immunogen
Antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of the human LASS6. The immunogen is located within the last 50 amino acids of LASS6.
Specificity
At least two isoforms of LASS6 are known to exist. This antibody is predicted not to cross-react with LASS5.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CERS6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 5 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
LASS6 Peptide (NBP1-76965PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for LASS6 Antibody

  • CerS6
  • LAG1 homolog, ceramide synthase 6
  • LAG1 longevity assurance homolog 6 (S. cerevisiae)
  • LAG1 longevity assurance homolog 6
  • longevity assurance homolog 6
  • MGC129949
  • MGC129950

Background

The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development. At least two isoforms of LASS6 are known to exist. This antibody is predicted not to cross-react with LASS5.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CERS6
Uniprot