LAP (TGF-beta 1) Antibody (7F6) - BSA Free

Western Blot: LAP (TGF-beta 1) Antibody (7F6) [NBP2-22114] - Western blot analysis using TGF beta 1 mAb against human LAP (TGF-beta 1) recombinant protein. (Expected MW is 41 kDa)

Immunohistochemistry-Paraffin: LAP (TGF-beta 1) Antibody (7F6) [NBP2-22114] - Immunohistochemical analysis of paraffin-embedded lymphoid tissue tissues using LAP (TGF-beta 1) mouse mAb with DAB staining.

Flow Cytometry: LAP (TGF-beta 1) Antibody (7F6) [NBP2-22114] - Flow cytometric analysis of A549 cells using LAP (TGF-beta 1) mouse mAb (green) and negative control (red).

Western Blot: LAP (TGF-beta 1) Antibody (7F6) [NBP2-22114] - Western blot analysis of human stomach tissue (A) and human small intestine tissue (B) using TGF beta 1 antibody (NBP2-22114) at 2 ug/ml.

Immunohistochemistry-Paraffin: LAP (TGF-beta 1) Antibody (7F6) [NBP2-22114] - Human tonsil. Image from verified customer review.

Immunohistochemistry-Paraffin: LAP (TGF-beta 1) Antibody (7F6) [NBP2-22114] - Immunohistochemical analysis of paraffin-embedded lung cancer tissues using LAP (TGF-beta 1) mouse mAb with DAB staining.

ELISA: LAP (TGF-beta 1) Antibody (7F6) [NBP2-22114] - Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng).

CD47 regulates thrombospondin-1, TGF-beta 1, and collagen deposition after injury. a Whole cell lysates from freshly isolated intestinal epithelial cells from Cd47f/f and Cd47 delta IEC mice were subjected to SDS–PAGE and immunoblot for thrombospondin-1/TSP-1, TGF-beta 1, and phosphorylated SMAD2 and SMAD3. Results are representative of three independent experiments. b Representative Masson’s trichrome staining of wounds beds and chronic DSS-colitis colons from Cd47f/f and Cd47 delta IEC mice. Scale bars = 50 μm. Results representative of three independent experiments with 5–7 mice per group. Source data are provided as a Source Data file Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/31676794), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Inhibition of ERK1/2 activation attenuates myocardial remodeling and inflammation in permanent MI.Trametinib- and vehicle-treated mice were studied for 7 days after permanent LAD ligation. (A) Relative mRNA expression analysis of Il6, Tnf, Ccl2, and Ccr2 from the infarcted myocardium. (B) Flow cytometry analysis of the infarcted myocardium obtained from vehicle- or trametinib-treated mice normalized to heart weight. Representative gating strategies for quantification of CD45+ leukocytes: CD45+CD90.2–B220–NK1.1–CD11b+ myelomonocytic cells, CD45+CD90.2–B220–NK1.1–CD11b+Ly6G–F4/80–Ly6Chi monocytes, and CD45+CD90.2–B220–NK1.1–CD11b+Ly6G–F4/80–Ly6Clo macrophages. (C) Protein expression analysis of p-ERK1/2 (normalized to total ERK1/2) and activated TGF-beta 1 (normalized to GAPDH) in infarcted myocardium obtained from vehicle- or trametinib-treated mice. IOD, integrated optical density. (D) Protein expression analysis of p-ERK1/2 (normalized to ERK1/2) and activated TGF-beta 1 (normalized to GAPDH) in PBMCs isolated from vehicle- or trametinib-treated mice. Ordinary 1-way ANOVA, Šidak’s multiple-comparison test; n = 4–6 animals per group. Data are shown as mean +/- SEM. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/36548062), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Inhibition of ERK1/2 activation attenuates myocardial remodeling and inflammation in permanent MI.Trametinib- and vehicle-treated mice were studied for 7 days after permanent LAD ligation. (A) Relative mRNA expression analysis of Il6, Tnf, Ccl2, and Ccr2 from the infarcted myocardium. (B) Flow cytometry analysis of the infarcted myocardium obtained from vehicle- or trametinib-treated mice normalized to heart weight. Representative gating strategies for quantification of CD45+ leukocytes: CD45+CD90.2–B220–NK1.1–CD11b+ myelomonocytic cells, CD45+CD90.2–B220–NK1.1–CD11b+Ly6G–F4/80–Ly6Chi monocytes, and CD45+CD90.2–B220–NK1.1–CD11b+Ly6G–F4/80–Ly6Clo macrophages. (C) Protein expression analysis of p-ERK1/2 (normalized to total ERK1/2) and activated TGF-beta 1 (normalized to GAPDH) in infarcted myocardium obtained from vehicle- or trametinib-treated mice. IOD, integrated optical density. (D) Protein expression analysis of p-ERK1/2 (normalized to ERK1/2) and activated TGF-beta 1 (normalized to GAPDH) in PBMCs isolated from vehicle- or trametinib-treated mice. Ordinary 1-way ANOVA, Šidak’s multiple-comparison test; n = 4–6 animals per group. Data are shown as mean +/- SEM. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/36548062), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

The upregulation of TGF beta 1/IGF-1/BDNF expression in the brain of AD mice by PBMT extended to promote adult hippocampal neurogenesis. A, B Western blotting analysis (A) and quantification (B) of TGF beta 1/IGF-1/BDNF expression in APP/PS1 and 3xTg-AD mouse brain after PBMT, (n = 3–4 per group). C The concentration of TGF beta 1/IGF-1/BDNF in brain tissues were measured by enzyme linked immunosorbent assay (ELISA), (n = 3–6 per group). D Representative images of Nestin+ (neural stem cell staining) and neuronal class-III beta -tubulin (Tuj1)+ (newborn neurons staining) expression cells in APP/PS1 and 3xTg-AD mouse hippocampal dentate gyrus (DG) at the end of PBMT. Scale bars, 50 μm. E Quantitative analyses of Nestin+ and Tuj1+ area in the hippocampal DG of each group, (n = 4 per group). F Quantitative analyses of the Nestin and Tuj1 mean fluorescence (MFI) in the brain tissues of each group after PBMT. The Nestin and Tuj1 MFI were detected by flow cytometer, (n = 5–6 per group). G Tuj1 antibody was used to staining the newborn neurons, and then, the expression of alpha -amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptors (AMPAR) and postsynaptic density protein 95 (PSD95) on Tuj1+ neurons were detected by flow cytometer. All quantifications are presented as mean +/- SEM and were analyzed by one-way ANOVA test; ***p < 0.001, **p < 0.01, *p < 0.05 versus WT group; ###p < 0.001, ##p < 0.01, #p < 0.05 versus indicated group Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/36217178), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

TF cytoplasmic domain phosphorylation–dependent increased TGF-beta 1 activation in clinical setting of MI.(A) Representative confocal images of phosphorylation status of TF in infarcted myocardium obtained from WT or TF delta CT mice after 7 days. Representative images and quantification of biological replicates. Kruskal-Wallis test and Dunn’s multiple-comparison test; n = 3–4 animals per group. Scale bars: 50 μm. (B) Representative immunofluorescence confocal microscopy images of CD45+ and CD45/p-TF double-positive cells in human myocardium specimens obtained from n = 5 nonischemic (NI) donor hearts and n = 7 IHF patients. Quantification of biological replicates. Mann-Whitney test. Scale bars: 50 μm. (C and D) Western blot analysis and quantification of human LV tissue obtained from n = 5 nonischemic donor hearts and n = 9 IHF patients for p-TF (normalized to total TF) and TF (C) or TGF-beta 1 (normalized to GAPDH) and p-SMAD2 (normalized to total SMAD2) (D). Mann-Whitney test. Data are shown as mean +/- SEM. *P < 0.05. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/36548062), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

A profibrotic MEK1/2–TGF-beta 1 pathway is linked to PAR2-mediated ROS signaling in monocytes.(A and B) Protein expression analysis of monocytes isolated from WT mice and pretreated in vitro with trametinib (10 μM) for 1 hour (A), or isolated from PAR2–/– versus WT mice (B). Cells were stimulated with an inflammatory cytokine cocktail containing IL-6, TNF-alpha , and CCL2 at a concentration of 20 ng/mL with and without hypoxia for 4 hours. Western blotting of p-ERK1/2 (normalized to total ERK1/2) and activated TGF-beta 1 (normalized to GAPDH). Ordinary 1-way ANOVA, Šidak’s multiple-comparison test; n = 5 replicates (2–3 mice were pooled for each sample). (C–E) PAR2fl/fl and PAR2fl/fl LysMCre littermates were subjected to permanent LAD ligation and investigated after 7 days; n = 5–10 animals per group. (C) Western blot analysis of activated TGF-beta 1 (normalized to GAPDH) and p-SMAD2 (normalized to total SMAD2) in the infarcted myocardium. Representative blots and quantification of biological replicates. (D) High-frequency ultrasound echocardiography obtained from PAR2fl/fl LysMCre and PAR2fl/fl littermate control mice with measurement of LVEF (%) and LVEDV (μL). Mann-Whitney test. (E) Kaplan-Meier survival analysis of permanently LAD-ligated PAR2fl/fl LysMCre and PAR2fl/fl littermate control mice over 7 days. Log-rank (Mantel-Cox) test. (F) Sirius red staining and deconvoluted images of fibrotic area on paraffin-embedded heart sections 4 weeks after permanent LAD ligation to induce IHF. Representative images and quantification of fibrotic areas normalized to surface area. Unpaired, 2-sided t test; n = 5 animals per group. Data are shown as mean +/- SEM. *P < 0.05, **P < 0.01, ****P < 0.0001. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/36548062), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

A profibrotic MEK1/2–TGF-beta 1 pathway is linked to PAR2-mediated ROS signaling in monocytes.(A and B) Protein expression analysis of monocytes isolated from WT mice and pretreated in vitro with trametinib (10 μM) for 1 hour (A), or isolated from PAR2–/– versus WT mice (B). Cells were stimulated with an inflammatory cytokine cocktail containing IL-6, TNF-alpha , and CCL2 at a concentration of 20 ng/mL with and without hypoxia for 4 hours. Western blotting of p-ERK1/2 (normalized to total ERK1/2) and activated TGF-beta 1 (normalized to GAPDH). Ordinary 1-way ANOVA, Šidak’s multiple-comparison test; n = 5 replicates (2–3 mice were pooled for each sample). (C–E) PAR2fl/fl and PAR2fl/fl LysMCre littermates were subjected to permanent LAD ligation and investigated after 7 days; n = 5–10 animals per group. (C) Western blot analysis of activated TGF-beta 1 (normalized to GAPDH) and p-SMAD2 (normalized to total SMAD2) in the infarcted myocardium. Representative blots and quantification of biological replicates. (D) High-frequency ultrasound echocardiography obtained from PAR2fl/fl LysMCre and PAR2fl/fl littermate control mice with measurement of LVEF (%) and LVEDV (μL). Mann-Whitney test. (E) Kaplan-Meier survival analysis of permanently LAD-ligated PAR2fl/fl LysMCre and PAR2fl/fl littermate control mice over 7 days. Log-rank (Mantel-Cox) test. (F) Sirius red staining and deconvoluted images of fibrotic area on paraffin-embedded heart sections 4 weeks after permanent LAD ligation to induce IHF. Representative images and quantification of fibrotic areas normalized to surface area. Unpaired, 2-sided t test; n = 5 animals per group. Data are shown as mean +/- SEM. *P < 0.05, **P < 0.01, ****P < 0.0001. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/36548062), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Myeloid cell–derived TF-PAR2 complex is required for TGF-beta 1 activation.(A) Confocal microscopy of myocardial cryosections obtained from n = 5 sham-operated and n = 5 LAD-ligated WT (C57BL/6J) mice at day 7. Representative images and quantification of TF+ cells costained for CD45. Unpaired, 2-sided t test. Scale bar: 50 μm. (B–D) TFfl/fl LysMCre and TFfl/fl littermates were subjected to permanent LAD ligation versus sham surgery and investigated after 7 days; n = 5–7 animals per group. (B) Protein expression analysis of p-ERK1/2 (normalized to total ERK1/2) in the infarcted myocardium. Ordinary 1-way ANOVA, Šidak’s multiple-comparison test. (C) Western blot analysis of activated TGF-beta 1 (normalized to GAPDH) and p-SMAD2 (normalized to total SMAD2) in the infarcted myocardium obtained from TFfl/fl LysMCre and TFfl/fl littermates. Representative blots and quantification of biological replicates. (D) High-frequency ultrasound echocardiography obtained from TFfl/fl LysMCre and TFfl/fl littermates. Ordinary 1-way ANOVA, Šidak’s multiple-comparison test. (E) Sirius red staining and deconvoluted images of fibrotic area on paraffin-embedded heart sections 4 weeks after permanent LAD ligation to induce IHF versus sham surgery. Representative images and quantification of fibrotic areas normalized to surface area. Ordinary 1-way ANOVA, Šidak’s multiple-comparison test; n = 5 animals per group. (F) Kaplan-Meier survival analysis of permanently LAD-ligated TFfl/fl LysMCre and TFfl/fl littermate mice over 4 weeks. Log-rank (Mantel-Cox) test; n = 10–15 animals per group. Data are shown as mean +/- SEM. *P < 0.05, **P < 0.01, ***P < 0.001. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/36548062), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Myeloid cell TF cytoplasmic domain phosphorylation mediates ERK1/2–TGF-beta 1–dependent cardiac remodeling in permanent LAD ligation.(A) Confocal microscopy of myocardial cryosections obtained from WT (C57BL/6J) and TF delta CT mice. Representative images and quantification of MFI of Ly6C+TGF beta -1+ and CD31+TGF-beta 1+ cells. Ordinary 1-way ANOVA, Šidak’s multiple-comparison test; n = 5 animals per group. Scale bars: 25 μm. (B) Mice with transplanted BM were subjected to permanent LAD ligation versus sham surgery and investigated 7 days later. Western blot analysis of NOX2 (normalized to GAPDH), p-ERK1/2 (normalized to total ERK1/2), and TGF-beta 1 (normalized to GAPDH) in infarcted myocardium obtained from chimeric mice. Ordinary 1-way ANOVA, Šidak’s multiple-comparison test; n = 5–7 animals per group. Data are shown as mean +/- SEM. *P < 0.05, **P < 0.01, ***P < 0.001. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/36548062), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

A profibrotic MEK1/2–TGF-beta 1 pathway is linked to PAR2-mediated ROS signaling in monocytes.(A and B) Protein expression analysis of monocytes isolated from WT mice and pretreated in vitro with trametinib (10 μM) for 1 hour (A), or isolated from PAR2–/– versus WT mice (B). Cells were stimulated with an inflammatory cytokine cocktail containing IL-6, TNF-alpha , and CCL2 at a concentration of 20 ng/mL with and without hypoxia for 4 hours. Western blotting of p-ERK1/2 (normalized to total ERK1/2) and activated TGF-beta 1 (normalized to GAPDH). Ordinary 1-way ANOVA, Šidak’s multiple-comparison test; n = 5 replicates (2–3 mice were pooled for each sample). (C–E) PAR2fl/fl and PAR2fl/fl LysMCre littermates were subjected to permanent LAD ligation and investigated after 7 days; n = 5–10 animals per group. (C) Western blot analysis of activated TGF-beta 1 (normalized to GAPDH) and p-SMAD2 (normalized to total SMAD2) in the infarcted myocardium. Representative blots and quantification of biological replicates. (D) High-frequency ultrasound echocardiography obtained from PAR2fl/fl LysMCre and PAR2fl/fl littermate control mice with measurement of LVEF (%) and LVEDV (μL). Mann-Whitney test. (E) Kaplan-Meier survival analysis of permanently LAD-ligated PAR2fl/fl LysMCre and PAR2fl/fl littermate control mice over 7 days. Log-rank (Mantel-Cox) test. (F) Sirius red staining and deconvoluted images of fibrotic area on paraffin-embedded heart sections 4 weeks after permanent LAD ligation to induce IHF. Representative images and quantification of fibrotic areas normalized to surface area. Unpaired, 2-sided t test; n = 5 animals per group. Data are shown as mean +/- SEM. *P < 0.05, **P < 0.01, ****P < 0.0001. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/36548062), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, Flow, IHC
• Clone: 7F6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

LAP (TGF-beta 1) Antibody (7F6) - BSA Free Summary

• Description: Novus Biologicals Mouse LAP (TGF-beta 1) Antibody (7F6) - BSA Free (NBP2-22114) is a monoclonal antibody validated for use in IHC, WB, ELISA and Flow. Anti-LAP (TGF-beta 1) Antibody: Cited in 18 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Purified recombinant fragment of human TGF beta 1 (amino acids 62-197) expressed in E. coli. [UniProt# P01137]
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TGFB1
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Flow Cytometry 1:200-1:400
  • Immunohistochemistry reported in scientific literature (PMID 30147399)
  • Immunohistochemistry-Paraffin reported by customer review
  • Western Blot 1:500-1:2000
• Theoretical MW: 44.3 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 26851347). Rat reactivity reported in scientific literature (PMID: 30147399).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Ammonium sulfate precipitation

Alternate Names for LAP (TGF-beta 1) Antibody (7F6) - BSA Free

• CED
• DPD1
• LAP (TGFbeta 1)
• LAP (TGF-beta 1)
• LAP
• TGFB
• TGFB1
• TGFbeta
• transforming growth factor beta 1

Background

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for LAP (TGF-beta 1) Antibody (NBP2-22114)(21)

Publications using NBP2-22114

• Abdelhady R, Sayed R, Younis N et al. Targeting JNK1/2 and P38 Mitogen‐Activated Protein Kinases With Pazopanib Mitigates Bleomycin‐Induced Lung Fibrosis Archiv der Pharmazie 2025-09-28 [PMID: 41017227]
• Lang M, Krump C, Meshcheryakova A et al. Microenvironmental and cell intrinsic factors governing human cDC2 differentiation and monocyte reprogramming Frontiers in Immunology 2023-07-19 [PMID: 37539048]
• Sholqamy M TGF- beta Paradox and the Progression of Osteoblastoma versus Osteosarcoma. Egyptian Dental Journal 2021-10-01
• Son M, Yim H, Lee Y et al. Pre- and Postnatal Fine Particulate Matter Exposure and Renal Fibrogenesis in Adult Male Rats: The Role of Vitamin D Supplementation. Current issues in molecular biology 2025-05-22 [PMID: 40699786]
• Esmail MM, Saeed NM, Hanna DMF et Al. Hepatoprotective and neuroprotective effects of quinacrine against bile duct ligation-induced hepatic encephalopathy in rats: Role of bone morphogenetic proteins signaling Life Sci 2024-11-12 [PMID: 39537098]
• Mousset A, Lecorgne E, Bourget I et al. Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-? activation Cancer cell 2023-04-10 [PMID: 37037615] (WB, Mouse)
• Garlapati V, Molitor M, Michna T et al. Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-?1-driven fibrotic remodeling in ischemic heart failure Journal of Clinical Investigation 2023-02-15 [PMID: 36548062]
• Wu X, Shen Q, Chang H et al. Promoted CD4(+) T cell-derived IFN-?/IL-10 by photobiomodulation therapy modulates neurogenesis to ameliorate cognitive deficits in APP/PS1 and 3xTg-AD mice Journal of Neuroinflammation 2022-10-10 [PMID: 36217178]
• Z Shen, W Luo, B Tan, K Nie, M Deng, S Wu, M Xiao, X Wu, X Meng, T Tong, C Zhang, K Ma, Y Liao, J Xu, X Wang Roseburia intestinalis stimulates TLR5-dependent intestinal immunity against Crohn&#039;s disease EBioMedicine, 2022-09-28;85(0):104285. 2022-09-28 [PMID: 36182776]
• Mohamed MZ, Abed El Baky MF, Ali ME, Hafez HM Aprepitant exerts anti-fibrotic effect via inhibition of TGF-beta/Smad3 pathway in bleomycin-induced pulmonary fibrosis in rats Environmental toxicology and pharmacology 2022-08-02 [PMID: 35931359] (IHC-P, Rat)
  
  Details:
  1:100 IHC-P
• Griffin J, Krolikowski J, Kounga K et al. Red Light Mitigates the Deteriorating Placental Extracellular Matrix in Late Onset of Preeclampsia and Improves the Trophoblast Behavior Journal of Pregnancy 2022-04-20 [PMID: 35494491] (IHC-Fr, Human)
• Malik MNH, Waqas SFH, Zeitvogel J et al. Congenital deficiency reveals critical role of ISG15 in skin homeostasis The Journal of clinical investigation 2021-11-30 [PMID: 34847081] (IF/IHC, Human)
• Singh J, Thachil T, Eapen M Et Al. Immunohistochemical investigation of cytokine expression levels as biomarkers in transrectal ultrasound-guided needle biopsy specimens of prostate adenocarcinoma Molecular and Clinical Oncology 2021-07-16 [PMID: 34405051] (IHC-P)
• Wang J, Lee CJ, Deci MB et al. MiR-101a loaded extracellular nanovesicles as bioactive carriers for cardiac repair Nanomedicine 2020-04-08 [PMID: 32278100] (IF/IHC, IHC-Fr, Mouse)
• Wang X, Jian X, Dou J et al. Decreasing Microtubule Actin Cross-Linking Factor 1 Inhibits Melanoma Metastasis by Decreasing Epithelial to Mesenchymal Transition Cancer Manag Res 2020-01-29 [PMID: 32099463] (WB, Mouse)
• Reed M, Luissint AC, Azcutia V et al. Epithelial CD47 is critical for mucosal repair in the murine intestine in vivo Nat Commun 2019-11-01 [PMID: 31676794] (WB, Mouse)
• Hendrijantini N, Kusumaningsih T, Rostiny R et al. A potential therapy of human umbilical cord mesenchymal stem cells for bone regeneration on osteoporotic mandibular bone Eur J Dent 2018-08-28 [PMID: 30147399] (IF/IHC, Rat)
• Awad SM, Ismail SA, Sayed DS et al. Suppression of transforming growth factor-beta1 expression in keloids after cryosurgery. Cryobiology. 2017-03-10 [PMID: 28288795] (IHC-P, Human)
• Hosseini H, Li Y, Kanellakis P et al. TollLike Receptor (TLR) 4 and MyD88 are Essential for Atheroprotection by Peritoneal B1a B Cells. Journal of the American Heart Association. 2016-11-14 [PMID: 27930350] (Mouse)
• Derricott H, Jones RL, Greenwood SL et al. Characterizing Villitis of Unknown Etiology and Inflammation in Stillbirth. The American Journal of Pathology. 2016-04-18 [PMID: 26851347] (IHC-P, Mouse)
• Makboul M, Makboul R, Abdelhafez AH et al. Evaluation of the effect of fractional CO2 laser on histopathological picture and TGF-b1 expression in hypertrophic scar. J Cosmet Dermatol. 2014-09-01 [PMID: 25196683]

Reviews for LAP (TGF-beta 1) Antibody (NBP2-22114) (3)

Average Rating: 3.7

(Based on 3 reviews)

We have 3 reviews tested in 2 species: Human, Mouse.

reviewed by: Shatovisha Dey WB Mouse 10/02/2020

Summary

• Application: Western Blot
• Sample Tested: Mouse Pancreas
• Species: Mouse
• Lot: 384830

reviewed by: Verified Customer IHC-P Human 10/28/2015

Summary

• Application: Immunohistochemistry-Paraffin
• Sample Tested: Human kidney
• Species: Human
• Lot: 130520

reviewed by: Hayley Derricott IHC-P Human 04/04/2014

Summary

• Application: Immunohistochemistry-Paraffin
• Sample Tested: human tonsil
• Species: Human
• Lot: 130102

FAQs for LAP (TGF-beta 1) Antibody (NBP2-22114). (Showing 1 - 1 of 1 FAQs).

1. Info regarding this product NBP2-22114SS, does this product cross reacts with Latent TGF-beta 1 also?
   • Based on the immunogen sequence, we predict it would cross react.

Bioinformatics

• Gene Symbol: TGFB1
• Entrez:
  • 7040(Human)
• Uniprot:
  • P01137(Human)