Reactivity | HuSpecies Glossary |
Clone | P3H9-2 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Alexa Fluor 350 |
Specificity | Detects human Laminin alpha 3/Laminin‑5 in Western blots. |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Storage | Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied |
Buffer | Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide |
Laminins are heterotrimeric, noncollagenous glycoproteins composed of alpha, beta and gamma chains. Through interactions with Integrins, Dystroglycan and other receptors, Laminins contribute to cell differentiation, cell shape and migration, and maintenance of tissue phenotypes and survival (1). Laminin-5, also known as Epiligrin, consists of an alpha 3, beta 3, and gamma 2 chain. It is abundant in transitional epithelium, stratified squamous epithelia, lung mucosa and other epithelial glands and plays an important role in the initiation and maintenance of epithelial cell anchorage to the underlying connective tissue (2, 3).
Secondary Antibodies |
Isotype Controls |
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