Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human endometrium shows moderate nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human cervix, uterine shows weak nuclear positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human rectum shows moderate nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human testis shows moderate nuclear positivity in cells in seminiferous ducts.
This antibody was developed against Recombinant Protein corresponding to amino acids: AQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHI
Predicted Species
Mouse (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KMT2D
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for KMT2D Antibody - BSA Free
AAD10
ALRALL1-related protein
CAGL114
EC 2.1.1.43
histone-lysine N-methyltransferase MLL2
KMT2D
Lysine N-methyltransferase 2B
MLL4
myeloid/lymphoid or mixed-lineage leukemia 2
Myeloid/lymphoid or mixed-lineage leukemia protein 2
TNRC21
trinucleotide repeat containing 21
Background
Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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