KMT2D Antibody

Images

 
Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human endometrium shows moderate nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human cervix, uterine shows weak nuclear positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human rectum shows moderate nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human testis shows moderate nuclear positivity in cells in seminiferous ducts.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

KMT2D Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: AQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHI
Predicted Species
Mouse (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MLL2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
KMT2D Protein (NBP1-89123PEP)
Publications
Read Publications using
NBP1-89123 in the following applications:

Reactivity Notes

Rat (84%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for KMT2D Antibody

  • AAD10
  • ALRALL1-related protein
  • CAGL114
  • EC 2.1.1.43
  • histone-lysine N-methyltransferase MLL2
  • KMT2D
  • Lysine N-methyltransferase 2B
  • MLL4
  • myeloid/lymphoid or mixed-lineage leukemia 2
  • Myeloid/lymphoid or mixed-lineage leukemia protein 2
  • TNRC21
  • trinucleotide repeat containing 21

Background

Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KMT2D Antibody (NBP1-89123)(4)

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Secondary Antibodies

 

Isotype Controls

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Array NBP1-89123

Bioinformatics Tool for KMT2D Antibody (NBP1-89123)

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Diseases for KMT2D Antibody (NBP1-89123)

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Bioinformatics

Gene Symbol MLL2