KIR2DL1/KIR2DS5 Antibody (143211) [Phycoerythrin]

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Human peripheral blood mononuclearcells (PBMCs) were stained with Mouse Anti-Human KIR2DL1/KIR2DS5PE‑conjugated Monoclonal Antibody (Catalog # FAB1844P) and MouseAnti-Human NCAM‑1/CD56 APC‑conjugated Monoclonal ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
143211
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

KIR2DL1/KIR2DS5 Antibody (143211) [Phycoerythrin] Summary

Immunogen
BaF3 mouse pro-B cell line transfected with human KIR2DL1/KIR2DS5
Accession # P43626
Specificity
Detects human KIR2DL1/KIR2DS5 on transfected cells. It does not stain cells transfected with KIR2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KIR2DL1
Purity
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB1844P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KIR2DL1/KIR2DS5 Antibody (143211) [Phycoerythrin]

  • CD158a
  • KIR2DL1/KIR2DS5

Background

KIR2DL1 is one of several immunoglobulin-like receptors expressed on NK cells that bind MHC class I molecules and transmit inhibitory signals. KIR2DL1 is specific for HLA-C alleles with Asn77 and Lys80.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KIR2DL1/KIR2DS5 Antibody (FAB1844P)(8)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(8)
All Applications
Filter By Species
Human
(8)
All Species
Showing Publications 1 - 8 of 8.
Publications using FAB1844P Applications Species
HC Tseng, W Xiong, S Badeti, Y Yang, M Ma, T Liu, CA Ramos, G Dotti, L Fritzky, JG Jiang, Q Yi, J Guarrera, WX Zong, C Liu, D Liu Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma Nat Commun, 2020;11(1):4810. 2020 [PMID: 32968061] (Flow Cytometry, Human) Flow Cytometry Human
MJW Sim, S Rajagopala, DM Altmann, RJ Boyton, PD Sun, EO Long Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):. 2019 [PMID: 31138701] (Flow Cytometry, Human) Flow Cytometry Human
AB Kristensen, SJ Kent, MS Parsons Contribution of NK cell education to both direct and anti-HIV-1 antibody-dependent NK cell functions J. Virol., 2018;0(0):. 2018 [PMID: 29514913] (Flow Cytometry, Human) Flow Cytometry Human
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol, 2013;43(2):480-7. 2013 [PMID: 23161492] (Flow Cytometry, Human) Flow Cytometry Human
Markel G, Seidman R, Besser MJ Natural killer lysis receptor (NKLR)/NKLR-ligand matching as a novel approach for enhancing anti-tumor activity of allogeneic NK cells. PLoS ONE, 2009;4(5):e5597. 2009 [PMID: 19440333] (Flow Cytometry, Human) Flow Cytometry Human
Cai L, Zhang Z, Zhou L, Wang H, Fu J, Zhang S, Shi M, Zhang H, Yang Y, Wu H, Tien P, Wang FS Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients. Clin. Immunol., 2008;129(3):428-37. 2008 [PMID: 18824414] (Flow Cytometry, Human) Flow Cytometry Human
Binyamin L, Alpaugh RK, Hughes TL, Lutz CT, Campbell KS, Weiner LM Blocking NK cell inhibitory self-recognition promotes antibody-dependent cellular cytotoxicity in a model of anti-lymphoma therapy. J. Immunol., 2008;180(9):6392-401. 2008 [PMID: 18424763] (Flow Cytometry, Human) Flow Cytometry Human
Ballan WM, Vu BA, Long BR, Loo CP, Michaelsson J, Barbour JD, Lanier LL, Wiznia AA, Abadi J, Fennelly GJ, Rosenberg MG, Nixon DF Natural killer cells in perinatally HIV-1-infected children exhibit less degranulation compared to HIV-1-exposed uninfected children and their expression of KIR2DL3, NKG2C, and NKp46 correlates with disease severity. J. Immunol., 2007;179(5):3362-70. 2007 [PMID: 17709553] (Flow Cytometry, Human) Flow Cytometry Human

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Bioinformatics

Gene Symbol KIR2DL1
Uniprot