CD161 Antibody (14F1F11)

Images

 
Western Blot: CD161 Antibody (14F1F11) [NBP2-14845] - Analysis of a partial CD161 recombinant protein using CD161 antibody at 1 ug/ml.
Immunohistochemistry-Paraffin: CD161 Antibody (14F1F11) [NBP2-14845] - Analysis using Azide Free version of NBP2-14845. CD161 in human kidney using CD161 antibody at 5 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clone
14F1F11
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

CD161 Antibody (14F1F11) Summary

Immunogen
Amino acids 68-225 of human CD161 were used as the immunogen for this antibody.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KLRB1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1-5 ug/ml
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml
Publications
Read Publication using
NBP2-14845 in the following applications:

  • IHC
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for CD161 Antibody (14F1F11)

  • CD161 antigen
  • CD161
  • CLEC5B
  • CLEC5BC-type lectin domain family 5 member B
  • HNKR-P1a
  • killer cell lectin-like receptor subfamily B member 1
  • killer cell lectin-like receptor subfamily B, member 1
  • KLRB1
  • Ly59
  • Natural killer cell surface protein P1A
  • NKR
  • NKRP1
  • NKR-P1
  • NKRP1A
  • NKR-P1AMGC138614
  • NKRP1ANKR

Background

CD161 is a C-Type Lectin Receptor, also known as NKR-P1A, previously found on NKT cells and subsets of T-cells. Phenotyping of cells that are functionally producing IL-17 has shown the one constant marker is CD161. While it had been shown previously that human CD4+ cells that produce both IL-17 and IFNg give rise to Th17/Th1 cells, indicating common etiology of these two T cell subsets, a clear marker for cells producing IL-17 is CD161. In fact, all cells characterized as the following subsets CD4+TCRab+, CD8+TCRab+, CD4-CD8-TCRab+, and CD4-CD8-TCRgd+ bearing CD161 also produce IL-17 but cells of these same phenotypes and functional marker which do not bear CD161 also do not produce IL-17. Induction of CD161 expression by transduction with RORC also induces IL-1R and IL-23R as well as the ability to produce IL-17. The ability to produce IL-17 and the induction of CD161 shows a strong dependency for RORC. Antibody to CD161 provides a probe for identifying IL-17 producing cells and offers a finer delineation of additional subsets derived from Th17 and their functional characteristics through cytokine mRNA expression or production.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB1058
Species: Hu
Applications: Flow, Block, CyTOF-ready
NBP1-19371
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Flow-IC
NBP2-45041
Species: Hu, Po
Applications: Flow, IHC, IHC-Fr, IF
NBP1-49045
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, CyTOF-ready, InhibTFunc
NBP2-15184
Species: Hu, Rt, Ze
Applications: WB, Simple Western, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, PAGE, Flow-CS
H00029121-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
MAB139
Species: Hu
Applications: WB, Flow, CostimT, CyTOF-ready, Neut
MAB12251
Species: Hu
Applications: Flow, CyTOF-ready
Supplier Logo

Publications for CD161 Antibody (NBP2-14845)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC.


Filter By Application
IHC
(1)
All Applications
Filter By Species
Human
(1)
All Species

Reviews for CD161 Antibody (NBP2-14845) (0)

There are no reviews for CD161 Antibody (NBP2-14845). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for CD161 Antibody (NBP2-14845) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-14845AF350
Alexa Fluor 405 NBP2-14845AF405
Alexa Fluor 488 NBP2-14845AF488
Alexa Fluor 532 NBP2-14845AF532
Alexa Fluor 594 NBP2-14845AF594
Alexa Fluor 647 NBP2-14845AF647
Alexa Fluor 700 NBP2-14845AF700
Alexa Fluor 750 NBP2-14845AF750
Biotin NBP2-14845B
DyLight 350 NBP2-14845UV
DyLight 405 NBP2-14845V
DyLight 488 NBP2-14845G
DyLight 550 NBP2-14845R
DyLight 594 NBP2-14845DL594
DyLight 650 NBP2-14845C
DyLight 680 NBP2-14845FR
DyLight 755 NBP2-14845IR
HRP NBP2-14845H
Janelia Fluor 549 NBP2-14845JF549
Janelia Fluor 646 NBP2-14845JF646

Additional CD161 Products

Bioinformatics Tool for CD161 Antibody (NBP2-14845)

Discover related pathways, diseases and genes to CD161 Antibody (NBP2-14845). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CD161 Antibody (NBP2-14845)

Discover more about diseases related to CD161 Antibody (NBP2-14845).
 

Pathways for CD161 Antibody (NBP2-14845)

View related products by pathway.

PTMs for CD161 Antibody (NBP2-14845)

Learn more about PTMs related to CD161 Antibody (NBP2-14845).
 

Research Areas for CD161 Antibody (NBP2-14845)

Find related products by research area.

Blogs on CD161

There are no specific blogs for CD161, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our CD161 Antibody (14F1F11) and receive a gift card or discount.

Bioinformatics

Gene Symbol KLRB1
Uniprot