NKG2A/CD159a/KLRC1 Antibody (131411) [Unconjugated]


Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM‑1/CD56 APC‑conjugated Monoclonal Antibody (Catalog # FAB2408A) and either (A) Mouse Anti-Human NKG2A/CD159a Monoclonal ...read more
HEK293 Human embryonic kidney cell line transfected with either (A) Human NKG2A/CD159a, or (B) Human NKG2B/CD159b and eGFP was stained with Mouse Anti-Human NKG2A/CD159a Monoclonal Antibody (Catalog # MAB1059) followed ...read more

Product Details

Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready

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NKG2A/CD159a/KLRC1 Antibody (131411) [Unconjugated] Summary

BaF3 mouse pro-B cell line transfected with human NKG2A and CD94
Recognizes the human NKG2A/CD94 heterodimer. It does not recognize the NKG2C/CD94 heterodimer or the CD94 homodimer.
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells
Read Publications using
MAB1059 in the following applications:

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NKG2A/CD159a/KLRC1 Antibody (131411) [Unconjugated]

  • CD159 antigen-like family member A
  • CD159a antigen
  • CD159a
  • C-lectin type II protein
  • killer cell lectin-like receptor subfamily C, member 1
  • Klrc1
  • MGC13374
  • natural killer cell lectin
  • natural killer group protein 2
  • NK cell receptor A
  • NKG2
  • NKG2-1/B activating NK receptor
  • NKG2A
  • NKG2-A
  • NKG2-A/B type II integral membrane protein
  • NKG2-A/B-activating NK receptor
  • NKG2-A/NKG2-B type II integral membrane protein
  • NKG2AMGC59791
  • NKG2-B


NKG2A, also known as CD159a, is a type II transmembrane receptor having a single extracellular lectin-like domain and a cytoplasmic ITIM motif. It associates with CD94 and is expressed on NK cells and some activated T cell populations. The NKG2A/CD94 complex delivers an inhibitory signal upon recognition of its ligand, HLA-E.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for NKG2A/CD159a/KLRC1 Antibody (MAB1059)(15)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 6 applications: Affinity Chromatography, ELISA Capture, Flow Cytometry, Functional Assay, Immunoprecipitation, Neutralization.

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Affinity Chromatography
ELISA Capture
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Showing Publications 1 - 10 of 15. Show All 15 Publications.
Publications using MAB1059 Applications Species
L Jiang, H Fei, X Jin, X Liu, C Yang, C Li, J Chen, A Yang, J Zhu, H Wang, X Fei, S Zhang Extracellular Vesicle-Mediated Secretion of HLA-E by Trophoblasts Maintains Pregnancy by Regulating the Metabolism of Decidual NK Cells International journal of biological sciences, 2021-10-22;17(15):4377-4395. 2021-10-22 [PMID: 34803505] (Flow Cytometry, Human) Flow Cytometry Human
GT Hò, AA Celik, T Huyton, W Hiemisch, R Blasczyk, GS Simper, C Bade-Doedi NKG2A/CD94 Is a New Immune Receptor for HLA-G and Distinguishes Amino Acid Differences in the HLA-G Heavy Chain Int J Mol Sci, 2020-06-19;21(12):. 2020-06-19 [PMID: 32575403] (Affinity Chromatography, ELISA Capture, Human) Affinity Chromatography, ELISA Capture Human
WC Pump, T Kraemer, T Huyton, GT Hò, R Blasczyk, C Bade-Doedi Between Innate and Adaptive Immune Responses: NKG2A, NKG2C, and CD8? T Cell Recognition of HLA-E Restricted Self-Peptides Acquired in the Absence of HLA-Ia Int J Mol Sci, 2019-03-22;20(6):. 2019-03-22 [PMID: 30909402] (Immunoprecipitation, Human) Immunoprecipitation Human
B Müller-Dur, J Grählert, OP Devine, AN Akbar, C Hess CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age Aging (Albany NY), 2019-01-27;11(2):724-740. 2019-01-27 [PMID: 30686790] (Flow Cytometry, Human) Flow Cytometry Human
H Sun, J Xu, Q Huang, M Huang, K Li, K Qu, H Wen, R Lin, M Zheng, H Wei, W Xiao, R Sun, Z Tian, C Sun Reduced CD160 expression contributes to impaired NK cell function and poor clinical outcomes in patients with HCC Cancer Res., 2018-09-19;0(0):. 2018-09-19 [PMID: 30232222] (Flow Cytometry, Human) Flow Cytometry Human
Y Xia, Q Zhang, Q Zhen, Y Zhao, N Liu, T Li, Y Hao, Y Zhang, C Luo, X Wu Negative regulation of tumor-infiltrating NK cell in clear cell renal cell carcinoma patients through the exosomal pathway Oncotarget, 2017-06-06;8(23):37783-37795. 2017-06-06 [PMID: 28384121] (Flow Cytometry, Human) Flow Cytometry Human
Zhao D, Xu A, Dai Z, Peng J, Zhu M, Shen J, Zheng Q, Ran Z WNT5A transforms intestinal CD8alphaalpha(+) IELs into an unconventional phenotype with pro-inflammatory features. BMC Gastroenterol, 2015-12-10;15(0):173. 2015-12-10 [PMID: 26652024] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Wang F, Zhou Y, Fu B, Wu Y, Zhang R, Sun R, Tian Z, Wei H Molecular signatures and transcriptional regulatory networks of human immature decidual NK and mature peripheral NK cells. Eur J Immunol, 2014-06-11;44(9):2771-84. 2014-06-11 [PMID: 24838931] (Flow Cytometry, Human) Flow Cytometry Human
Serrano-Pertierra E, Cernuda-Morollon E, Brdicka T, Hooejsi V, Lopez-Larrea C L-plastin is involved in NKG2D recruitment into lipid rafts and NKG2D-mediated NK cell migration. J Leukoc Biol, 2014-05-06;96(3):437-45. 2014-05-06 [PMID: 24803550] (Neutralization, Human) Neutralization Human
Nachmani D, Zimmermann A, Oiknine Djian E, Weisblum Y, Livneh Y, Khanh Le V, Galun E, Horejsi V, Isakov O, Shomron N, Wolf D, Hengel H, Mandelboim O MicroRNA editing facilitates immune elimination of HCMV infected cells. PLoS Pathog, 2014-02-27;10(2):e1003963. 2014-02-27 [PMID: 24586166] (Flow Cytometry, Human) Flow Cytometry Human
Show All 15 Publications.

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Gene Symbol KLRC1