KIR2DL3/CD158b2 Antibody (180701) [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-reported
Clone
180701
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

KIR2DL3/CD158b2 Antibody (180701) [Unconjugated] Summary

Immunogen
BaF3 mouse pro-B cell line transfected with human KIR2DL3/CD158b2
Accession # P43628
Specificity
Detects human KIR2DL3/CD158b2. Stains BaF3 cells transfected with human KIR2DL3 in flow cytometry. Does not stain BaF3 cells transfected with KIR2DL1, 2DL2, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
KIR2DL3
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 2.5 ug/10^6 cells
  • CyTOF-reported
Publications
Read Publications using
MAB2014 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KIR2DL3/CD158b2 Antibody (180701) [Unconjugated]

  • CD158 antigen-like family member B2
  • CD158b2 antigen
  • CD158b2
  • CD158B2CD158b
  • cl-6
  • killer cell immunoglobulin-like receptor 2DL3
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
  • Killer inhibitory receptor cl 2-3
  • KIR-023GB
  • KIR2DL3
  • KIRCL23
  • KIR-K7b
  • KIR-K7c
  • MGC129943
  • MHC class I NK cell receptor
  • natural killer associated transcript 2
  • natural killer cell inhibitory receptor KIR2DL3
  • Natural killer-associated transcript 2
  • NKAT
  • NKAT2
  • NKAT-2
  • NKAT2A
  • nkat2b
  • NKAT2GL183
  • NK-receptor
  • p58 natural killer cell receptor clone CL-6
  • p58 NK receptor CL-6
  • p58
  • p58.2 MHC class-I specific NK receptor
  • p58.2 MHC class-I-specific NK receptor

Background

KIR2DL3 is one of several immunoglobulin-like receptors expressed on NK and T cells that bind MHC class I molecules and regulate killer cell activity. KIR2DL3 interacts specifically with HLA-Cw3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KIR2DL3/CD158b2 Antibody (MAB2014)(7)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: CyTof, Flow, Flow control.


Filter By Application
CyTof
(1)
Flow
(5)
Flow control
(1)
All Applications
Filter By Species
Human
(7)
All Species
Showing Publications 1 - 7 of 7.
Publications using MAB2014 Applications Species
HIV-1 Control by NK Cells via Reduced Interaction between KIR2DL2 and HLA-C(?)12:02/C(?)14:03 Cell Rep, 2016;17(9):2210-2220. 2016 [PMID: 27880898] (Flow,, Human) Flow Human
NK Cell Responses to Human Tick-Borne Encephalitis Virus Infection J Immunol, 2016;0(0):. 2016 [PMID: 27543616] (Flow,, Human) Flow Human
Horowitz A, Guethlein L, Nemat-Gorgani N, Norman P, Cooley S, Miller J, Parham P Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation. J Immunol, 2015;195(9):4524-36. 2015 [PMID: 26416275] (CyTof,, Human) CyTof Human
Sharkey A, Xiong S, Kennedy P, Gardner L, Farrell L, Chazara O, Ivarsson M, Hiby S, Colucci F, Moffett A Tissue-Specific Education of Decidual NK Cells. J Immunol, 2015;195(7):3026-32. 2015 [PMID: 26320253] (Flow,, Human) Flow Human
Enqvist M, Ask E, Forslund E, Carlsten M, Abrahamsen G, Beziat V, Andersson S, Schaffer M, Spurkland A, Bryceson Y, Onfelt B, Malmberg K Coordinated expression of DNAM-1 and LFA-1 in educated NK cells. J Immunol, 2015;194(9):4518-27. 2015 [PMID: 25825444] (Flow,, Human) Flow Human
Holmes T, Wilson E, Black E, Benest A, Vaz C, Tan B, Tanavde V, Cook G Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT. Proc Natl Acad Sci U S A, 2014;111(52):E5688-96. 2014 [PMID: 25512551] (Flow control,, Human) Flow control Human
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol, 2013;43(2):480-7. 2013 [PMID: 23161492] (Flow,, Human) Flow Human

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KIR2DL3
Entrez
Uniprot