KIR2DL3/CD158b2 Antibody (180701) [Unconjugated]

Images

 
Human peripheral blood mononuclear cells (PBMCs) were stained with (A) Mouse Anti-Human KIR2DL3/CD158b2 Monoclonal Antibody (Catalog # MAB2014) or (B) Isotype Control Antibody (Catalog # MAB003) followed by anti-Mouse ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-reported
Clone
180701
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

KIR2DL3/CD158b2 Antibody (180701) [Unconjugated] Summary

Immunogen
BaF3 mouse pro-B cell line transfected with human KIR2DL3/CD158b2
Accession # P43628
Specificity
Detects human KIR2DL3/CD158b2. Stains BaF3 cells transfected with human KIR2DL3 in flow cytometry. Does not stain BaF3 cells transfected with KIR2DL1, 2DL2, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
Details of Functionality
ActivityAssaywCitation not found None
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
KIR2DL3
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25 ug/10^6 cells
  • CyTOF-reported
Publications
Read Publications using
MAB2014 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KIR2DL3/CD158b2 Antibody (180701) [Unconjugated]

  • CD158 antigen-like family member B2
  • CD158b2 antigen
  • CD158b2
  • CD158B2CD158b
  • cl-6
  • killer cell immunoglobulin-like receptor 2DL3
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
  • Killer inhibitory receptor cl 2-3
  • KIR-023GB
  • KIR2DL3
  • KIRCL23
  • KIR-K7b
  • KIR-K7c
  • MGC129943
  • MHC class I NK cell receptor
  • natural killer associated transcript 2
  • natural killer cell inhibitory receptor KIR2DL3
  • Natural killer-associated transcript 2
  • NKAT
  • NKAT2
  • NKAT-2
  • NKAT2A
  • nkat2b
  • NKAT2GL183
  • NK-receptor
  • p58 natural killer cell receptor clone CL-6
  • p58 NK receptor CL-6
  • p58
  • p58.2 MHC class-I specific NK receptor
  • p58.2 MHC class-I-specific NK receptor

Background

KIR2DL3 is one of several immunoglobulin-like receptors expressed on NK and T cells that bind MHC class I molecules and regulate killer cell activity. KIR2DL3 interacts specifically with HLA-Cw3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KIR2DL3/CD158b2 Antibody (MAB2014)(7)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: CyTof, Flow Cytometry, Flow Cytometry Control.


Filter By Application
CyTof
(1)
Flow Cytometry
(5)
Flow Cytometry Control
(1)
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Filter By Species
Human
(7)
All Species
Showing Publications 1 - 7 of 7.
Publications using MAB2014 Applications Species
HIV-1 Control by NK Cells via Reduced Interaction between KIR2DL2 and HLA-C(?)12:02/C(?)14:03 Cell Rep, 2016;17(9):2210-2220. 2016 [PMID: 27880898] (Flow Cytometry, Human) Flow Cytometry Human
NK Cell Responses to Human Tick-Borne Encephalitis Virus Infection J Immunol, 2016;0(0):. 2016 [PMID: 27543616] (Flow Cytometry, Human) Flow Cytometry Human
Horowitz A, Guethlein L, Nemat-Gorgani N, Norman P, Cooley S, Miller J, Parham P Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation. J Immunol, 2015;195(9):4524-36. 2015 [PMID: 26416275] (CyTof, Human) CyTof Human
Sharkey A, Xiong S, Kennedy P, Gardner L, Farrell L, Chazara O, Ivarsson M, Hiby S, Colucci F, Moffett A Tissue-Specific Education of Decidual NK Cells. J Immunol, 2015;195(7):3026-32. 2015 [PMID: 26320253] (Flow Cytometry, Human) Flow Cytometry Human
Enqvist M, Ask E, Forslund E, Carlsten M, Abrahamsen G, Beziat V, Andersson S, Schaffer M, Spurkland A, Bryceson Y, Onfelt B, Malmberg K Coordinated expression of DNAM-1 and LFA-1 in educated NK cells. J Immunol, 2015;194(9):4518-27. 2015 [PMID: 25825444] (Flow Cytometry, Human) Flow Cytometry Human
Holmes T, Wilson E, Black E, Benest A, Vaz C, Tan B, Tanavde V, Cook G Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT. Proc Natl Acad Sci U S A, 2014;111(52):E5688-96. 2014 [PMID: 25512551] (Flow Cytometry Control, Human) Flow Cytometry Control Human
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol, 2013;43(2):480-7. 2013 [PMID: 23161492] (Flow Cytometry, Human) Flow Cytometry Human

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB2014U
Alexa Fluor 405 FAB2014V
Alexa Fluor 488 FAB2014G
Alexa Fluor 594 FAB2014T
Alexa Fluor 647 FAB2014R
Alexa Fluor 700 FAB2014N
Alexa Fluor 750 FAB2014S
Allophycocyanin FAB2014A
Allophycocyanin FAB2014A
Fluorescein FAB2014F
Fluorescein FAB2014F
Phycoerythrin FAB2014P
Phycoerythrin FAB2014P

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Bioinformatics

Gene Symbol KIR2DL3
Uniprot