Kallikrein 4/Prostase/EMSP1 Antibody - BSA Free

Western Blot: Kallikrein 4/Prostase/EMSP1 Antibody [NB200-134] - Analysis of KLK-L1 in RL95-2 (endometrial cancer cell lines, lane 1) and KLE (lane 2) using NB200-134 at 1:1000 dilution.

• Reactivity: Hu
• Applications: WB, ELISA, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Kallikrein 4/Prostase/EMSP1 Antibody - BSA Free Summary

• Immunogen: A synthetic peptide correspdonding to residues 242-254 [KFTEWIEKTVQAS] of the human 39 kDa LKL-L1 protein.
• Specificity: Reacts with residues 242-254 [KFTEWIEKTVQAS] of the human 39 kDa LKL-L1 protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KLK4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:500-1:1000
• Application Notes: Western blot - Use at 1:500 to 1:1,000 dilution. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Theoretical MW: 39 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Kallikrein 4/Prostase/EMSP1 Antibody - BSA Free

• AI2A1
• ARM1
• EC 3.4.21
• EC 3.4.21.-
• EMSP
• EMSP1
• EMSP1MGC116827
• Enamel matrix serine proteinase 1
• kallikrein 4 (prostase, enamel matrix, prostate)
• Kallikrein 4
• kallikrein-4
• Kallikrein-like protein 1
• kallikrein-related peptidase 4
• KLK4
• KLK-L1MGC116828
• Prostase
• PRSS17enamel matrix serine protease 1
• PSTSandrogen-regulated message 1
• Serine protease 17

Background

Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. A novel Kallikrein gene Prostase/KLK-L1 (also known as KLK4) is expressed and is up-regulated by androgens and progestins. KLK-L1 may be involved in the pathogenesis and/or progression of prostate, breast, and possibly other malignancies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KLK4
• Entrez:
  • 9622(Human)