KA2/GRIK5/Glutamate Receptor KA2 Antibody

Images

 
Western Blot: KA2/GRIK5/Glutamate Receptor KA2 Antibody [NBP1-76853] - Human brain tissue lysate with Grik5 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: KA2/GRIK5/Glutamate Receptor KA2 Antibody [NBP1-76853] - Human Brain cells.
Immunohistochemistry-Paraffin: KA2/GRIK5/Glutamate Receptor KA2 Antibody [NBP1-76853] - Human brain tissue using Glutamate receptor KA2 antibody at 2.5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

KA2/GRIK5/Glutamate Receptor KA2 Antibody Summary

Immunogen
Antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Grik5. The immunogen is located within the last 50 amino acids of Grik5.
Specificity
This Grik5 antibody does not cross-react with Grik4.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRIK5
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/mL
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
KA2/GRIK5/Glutamate Receptor KA2 Peptide (NBP1-76853PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for KA2/GRIK5/Glutamate Receptor KA2 Antibody

  • EAA2
  • Excitatory amino acid receptor 2
  • GluK5
  • glutamate receptor KA2
  • Glutamate receptor KA-2
  • glutamate receptor, ionotropic kainate 5
  • glutamate receptor, ionotropic, kainate 5
  • GRIK2
  • GRIK5
  • KA2/GRIK5
  • KA2GRIK2

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik5, also known as kainate-preferring glutamate recptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (also known as KA1). Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2. In Grik2- but not Grik1-null mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface. This Grik5 antibody does not cross-react with Grik4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol GRIK5
Entrez
Uniprot