GluR7/GRIK3 Antibody

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-Fr, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

GluR7/GRIK3 Antibody Summary

Immunogen
A synthetic peptide from c-terminal region of human GRIK3 (GLUR7, Glutamate receptor 7) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity
Specific for GRIK3.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRIK3
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:300-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Human, mouse, rat. Other species not yet tested.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute with 0.1 ml sterilized water to desired concentration.

Alternate Names for GluR7/GRIK3 Antibody

  • EAA5
  • Excitatory amino acid receptor 5
  • GLR7
  • GluK3
  • GluR7
  • gluR-7
  • GluR7a
  • GLUR7dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7))
  • Glutamate receptor 7
  • glutamate receptor, ionotropic kainate 3
  • glutamate receptor, ionotropic, kainate 3
  • GRIK3

Background

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brain stem whereas the four epsilon subunits display limited distribution

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol GRIK3
Entrez