Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
GRIK5 (Glutamate receptor, ionotropic kainate 5) is a
receptor for glutamate and is one of the 5 types of kainate receptor subunits. L-Glutamate acts as an excitatory
neurotransmitter at many synapses in the CNS. The GRIK5 protein forms
functional heteromic kainate-preferring ionic channels with the subunits
encoded by related gene family members. Kainate
receptors have both presynaptic and postsynaptic actions and a limited
distribution in the brain. Kainate receptors have been shown to have
connections with several neurological diseases and conditions. There is linkage to schizophrenia,
depression, autism, Huntington's, bipolar disorder, and epilepsy among others. KA2 is relatively abundant in all areas of
the brain, most notably in dentate gyrus, pyramidal neurons of CA3, cerebellar
granule cells, as well as being present in superficial and deep laminae of the
neocortex.
Bioinformatics
| Uniprot |
Human
|
| Product By Gene ID |
2901 |
| Alternate Names |
- EAA2
- Excitatory amino acid receptor 2
- GluK5
- glutamate receptor KA2
- Glutamate receptor KA-2
- glutamate receptor, ionotropic kainate 5
- glutamate receptor, ionotropic, kainate 5
- GRIK2
- GRIK5
- KA2/GRIK5
- KA2GRIK2
|
![Immunohistochemistry KA2/GRIK5/Glutamate Receptor KA2 Antibody (2916E) [Unconjugated]](http://images.novusbio.com/fullsize/mab113341_human-ka2-grik5-mab-clone-2916e-immunohistochemistry-111020239294..jpg)
