Integrin alpha V/CD51 Antibody (S03-6E3)

Western Blot: Integrin alpha V/CD51 Antibody (S03-6E3) [NBP3-19510] - Western blot detection of Integrin alpha V/CD51 in C6, 3T3, Hela cell lysates using NBP3-19510 (1:1000 diluted). Predicted band size: 87kDa. Observed band size: 135kDa.

Immunohistochemistry-Paraffin: Integrin alpha V/CD51 Antibody (S03-6E3) [NBP3-19510] - Immunohistochemistry of Integrin alpha V/CD51 in paraffin-embedded Human tonsil using NBP3-19510 at dilution 1/100

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: S03-6E3
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.3 mg/ml

Integrin alpha V/CD51 Antibody (S03-6E3) Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant protein of human Integrin alpha V/CD51 (Uniprot # P06756)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: ITGAV
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1/20-1/500
  • Immunohistochemistry-Paraffin
  • Western Blot 1/1000
• Theoretical MW: 135 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Concentration: 0.3 mg/ml
• Purity: Affinity purified

Alternate Names for Integrin alpha V/CD51 Antibody (S03-6E3)

• antigen identified by monoclonal L230
• CD51 antigen
• CD51
• Integrin alpha V
• integrin alpha-V
• integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
• ITGAV
• MSK8
• Vitronectin Receptor alpha
• Vitronectin receptor subunit alpha
• VNRA
• VNRADKFZp686A08142

Background

Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ITGAV