ILVBL Antibody - BSA Free

Western Blot: ILVBL Antibody [NBP1-78433] - Analysis of IVLBL in overexpression lysate.

Western Blot: ILVBL Antibody [NBP1-78433] - Analysis of ILVBL in human kidney tissue lysate.

• Reactivity: Hu
• Applications: WB, ICC/IF (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.20 mg/ml

ILVBL Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit ILVBL Antibody - BSA Free (NBP1-78433) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A synthetic peptide made to an internal portion of the human ILVBL protein (between residues 350-500) [UniProt A1L0T0]
• Localization: Membrane; Single-pass membrane protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ILVBL
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Application Notes: This ILVBL antibody is useful for Western Blot, where a band is seen ~67 kDa in human kidney tissue lysate and ILVBL overexpression lysates.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS and 30% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 0.20 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ILVBL Antibody - BSA Free

• acetolactate synthase homolog
• acetolactate synthase-like protein
• AHASFLJ39061,209L8
• EC 2.2.1
• EC 2.2.1.-
• ILV2H
• ilvB (bacterial acetolactate synthase)-like
• IlvB-like protein
• MGC1269
• MGC19535

Background

ILVBL (IHAS) is a ubiquitiously expressed 68 kDa membrane protein which belongs to a family of thiamine pyrophosate-binding proteins. While ILVB is known to be involved in the initial steps of branched chain amino acid synthesis, the exact role of this protein in mammals is not known. However, the gene does show similarity to the acetolactate synthase enzyme found in bacteria. Recently investigators mapped the ILVBL gene to the 19p13.1 chromosome. This region coincides with the CADASIL critical region, which is an autosomal dominant condition that results in infarcts of the subcortical regions of the brain leading to dementia. However, there were no mutations in this gene of CADISIL patients, so its role, if any, is not known (PMID:8954801).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ILVBL
• Entrez:
  • 10994(Human)
• Uniprot:
  • A1L0T0(Human)