ILVBL Antibody [DyLight 488]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 488

ILVBL Antibody [DyLight 488] Summary

• Immunogen: A synthetic peptide made to an internal portion of the human ILVBL protein (between residues 350-500) [UniProt A1L0T0]
• Localization: Membrane; Single-pass membrane protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ILVBL
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Application Notes: This ILVBL antibody is useful for Western Blot, where a band is seen ~67 kDa in human kidney tissue lysate and ILVBL overexpression lysates.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ILVBL Antibody [DyLight 488]

• acetolactate synthase homolog
• acetolactate synthase-like protein
• AHASFLJ39061,209L8
• EC 2.2.1
• EC 2.2.1.-
• ILV2H
• ilvB (bacterial acetolactate synthase)-like
• IlvB-like protein
• MGC1269
• MGC19535

Background

ILVBL (IHAS) is a ubiquitiously expressed 68 kDa membrane protein which belongs to a family of thiamine pyrophosate-binding proteins. While ILVB is known to be involved in the initial steps of branched chain amino acid synthesis, the exact role of this protein in mammals is not known. However, the gene does show similarity to the acetolactate synthase enzyme found in bacteria. Recently investigators mapped the ILVBL gene to the 19p13.1 chromosome. This region coincides with the CADASIL critical region, which is an autosomal dominant condition that results in infarcts of the subcortical regions of the brain leading to dementia. However, there were no mutations in this gene of CADISIL patients, so its role, if any, is not known (PMID:8954801).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ILVBL