PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C)

Images

 
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node. In benign lymph ...read more
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more
Immunohistochemistry-Paraffin: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Analysis of Thymidine Phosphorylase formalin-fixed paraffin embedded human breast carcinoma.
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P, IP
Clone
PGF 44C
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) Summary

Immunogen
Full length human protein in E. coli
Localization
Cytoplasmic and nuclear.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TYMP
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10 - 1:500
Application Notes
PGF 44C blocks enzyme activity.
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
PD-ECGF/Thymidine Phosphorylase Knockout HeLa Cell Lysate
Publications
Read Publication using NB100-2737.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Notes

Positive control(s): HUVEC cell or breast carcinoma.

Alternate Names for PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C)

  • dThdPase
  • EC 2.4.2
  • EC 2.4.2.4
  • ECGF
  • ECGF1
  • ECGF1TP
  • endothelial cell growth factor 1 (platelet-derived)
  • Gliostatin
  • hPD-ECGF
  • MEDPS1
  • MNGIE
  • MTDPS1
  • PDECGF
  • PD-ECGF
  • Platelet-derived endothelial cell growth factor
  • TdRPase
  • Thymidine Phosphorylase
  • TPase
  • TYMP

Background

Platelet - derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PD-ECGF/Thymidine Phosphorylase Antibody (NB100-2737)(1)

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for PD-ECGF/Thymidine Phosphorylase Antibody (NB100-2737) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NB100-2737AF350
Alexa Fluor 405 NB100-2737AF405
Alexa Fluor 488 NB100-2737AF488
Alexa Fluor 532 NB100-2737AF532
Alexa Fluor 594 NB100-2737AF594
Alexa Fluor 647 NB100-2737AF647
Alexa Fluor 700 NB100-2737AF700
Alexa Fluor 750 NB100-2737AF750
Biotin NB100-2737B
DyLight 350 NB100-2737UV
DyLight 405 NB100-2737V
DyLight 488 NB100-2737G
DyLight 550 NB100-2737R
DyLight 594 NB100-2737DL594
DyLight 650 NB100-2737C
DyLight 680 NB100-2737FR
DyLight 755 NB100-2737IR
FITC NB100-2737F
HRP NB100-2737H
Janelia Fluor 549 NB100-2737JF549
Janelia Fluor 646 NB100-2737JF646

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Bioinformatics

Gene Symbol TYMP
Entrez