PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) - BSA Free

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Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node. In benign lymph ...read more
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more
Immunohistochemistry-Paraffin: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Analysis of Thymidine Phosphorylase formalin-fixed paraffin embedded human breast carcinoma.
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P, IP
Clone
PGF 44C
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) - BSA Free Summary

Immunogen
Full length human protein in E. coli
Localization
Cytoplasmic and nuclear.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TYMP
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:100-1:2000
Application Notes
PGF 44C blocks enzyme activity.
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NB100-2737.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Notes

Positive control(s): HUVEC cell or breast carcinoma.

Alternate Names for PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) - BSA Free

  • dThdPase
  • EC 2.4.2
  • EC 2.4.2.4
  • ECGF
  • ECGF1
  • ECGF1TP
  • endothelial cell growth factor 1 (platelet-derived)
  • Gliostatin
  • hPD-ECGF
  • MEDPS1
  • MNGIE
  • MTDPS1
  • PDECGF
  • PD-ECGF
  • Platelet-derived endothelial cell growth factor
  • TdRPase
  • Thymidine Phosphorylase
  • TPase
  • TYMP

Background

Platelet - derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PD-ECGF/Thymidine Phosphorylase Antibody (NB100-2737)(1)

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics Tool for PD-ECGF/Thymidine Phosphorylase Antibody (NB100-2737)

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Bioinformatics

Gene Symbol TYMP
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