IL-4 Antibody (3010) [Allophycocyanin]

• Reactivity: Hu
• Applications: WB, ELISA, ELISA(Cap), ELISA(Det)
• Clone: 3010
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

IL-4 Antibody (3010) [Allophycocyanin] Summary

• Immunogen: E. coli-derived recombinant human IL‑4
  His25-Ser153
  Accession # P05112.1
• Specificity: Detects human IL-4 in ELISAs and Western blots. In sandwich ELISAs, no cross-reactivity or interference was observed with recombinant human (rh) IL‑1 alpha , rhIL‑1 beta , rhIL‑2, rhIL-3, rhIL-6, rhIL-7, rhIL-8, rhG-CSF, rhGM-CSF, rhTNF-alpha , rhTNF‑ beta , rhLIF, rhTGF‑ beta 1, recombinant mouse (rm) IL‑1 beta , rmIL-6, rmIL-7, rmGM-CSF, bovine FGF acidic, bovine FGF basic, porcine PDGF, human TGF‑ beta 1, porcine TGF‑ beta 1.2, and porcine TGF‑ beta 2.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL4
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for IL-4 Antibody (3010) [Allophycocyanin]

• B cell growth factor 1
• BCDF
• B-cell stimulatory factor 1
• BCGF1
• BCGF-1
• binetrakin
• BSF1
• BSF-1
• IL4
• IL-4
• IL-4B_cell stimulatory factor 1
• IL4E12
• interleukin 4
• interleukin-4
• Lymphocyte stimulatory factor 1
• MGC79402
• pitrakinra

Background

IL-4 (Interleukin 4, B cell stimulatory factor) is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. IL-4 has many different functions including promoting proliferation and differentiation of immunologically competent cells. One of its main functions is regulating differentiation of naive CD4+ T cells into helper Th2 cells, the other main function is regulating B cells IgE and IgG1 production. Human IL-4 shows 50% homology with mouse IL-4, but its activities are species-specific and human IL-4 shows no activity on murine and rat cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL4