We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

IL-4 Products

Antibodies
IL-4 Antibody (30340) [Unconj ...
IL-4 Antibody (30340) [Unconjugated]
MAB404
404-ML) stimulates proliferation in the HT-2 mouse T cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Rat Anti-Mouse IL-4 (7.5 ng/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse IL-4 Monoclonal Antibody (Catalog # MAB404). The ND50 is typically 0.1-0.6 µg/mL." class="big_lightbox" target="_blank"> Neutralization IL-4 Antibody (30340) [Unconjugated]
404-ML) was serially diluted and captured by Rat Anti-Mouse IL‑4 Monoclonal Antibody (Catalog # MAB404) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Mouse IL‑4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-404-NA) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank"> ELISA IL-4 Antibody (30340) [Unconjugated]
Species: Mu
Applications: WB, B/N, ELISA(Cap)
Host: Rat Monoclonal
IL-4 Antibody (34019) [Unconj ...
IL-4 Antibody (34019) [Unconjugated]
MAB204
204-IL) stimulates proliferation in the TF-1 human erythroleukemic cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human IL-4 (0.5 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human IL-4 Monoclonal Antibody (Catalog # MAB204). The ND50 is typically 0.5-1.5 µg/mL." class="big_lightbox" target="_blank"> Neutralization IL-4 Antibody (34019) [Unconjugated]
Species: Hu
Applications: WB, B/N
Host: Mouse Monoclonal
IL-4 Antibody (3010) [Unconju ...
IL-4 Antibody (3010) [Unconjugated]
MAB604
204-IL) was serially diluted and captured by Mouse Anti-Human IL‑4 Monoclonal Antibody (Catalog # MAB604) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human IL‑4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-204-NA) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank"> ELISA IL-4 Antibody (3010) [Unconjugated]
Species: Hu
Applications: WB, ELISA(Cap)
Host: Mouse Monoclonal
ELISA Kits
Mouse IL-4 Quantikine ELISA K ...
Mouse IL-4 Quantikine ELISA Kit, 2...
M4000B
Species: Mu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Mouse IL-4 DuoSet ELISA, 15 P ...
Mouse IL-4 DuoSet ELISA, 15 Plate
DY404
Species: Mu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Human IL-4 DuoSet ELISA, 15 P ...
Human IL-4 DuoSet ELISA, 15 Plate
DY204
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Proteins
Recombinant Human IL-4 (CHO-e ...
Recombinant Human IL-4 (CHO-expres...
6507-IL
Species: Hu
Applications: Bioactivity
Recombinant Mouse IL-4 Protei ...
Recombinant Mouse IL-4 Protein
404-ML
Species: Mu
Applications: Bioactivity
Recombinant Human IL-4 Protei ...
Recombinant Human IL-4 Protein
204-IL
BT-004). It has equivalent bioactivity to Recombinant Human IL-4 (Catalog # 204-IL). It combines R&D Systems quality with scalability that allows for a solid supply chain. Both Recombinant Human IL-4 proteins are measured in a cell proliferation assay using TF-1 human erythroleukemic cell line." class="big_lightbox" target="_blank"> Bioactivity IL-4 [Unconjugated]
Species: Hu
Applications: Bioactivity

Description

IL-4 (Interleukin 4, B cell stimulatory factor) is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. IL-4 has many different functions including promoting proliferation and differentiation of immunologically competent cells. One of its main functions is regulating differentiation of naive CD4+ T cells into helper Th2 cells, the other main function is regulating B cells IgE and IgG1 production. Human IL-4 shows 50% homology with mouse IL-4, but its activities are species-specific and human IL-4 shows no activity on murine and rat cells.

Bioinformatics

Entrez Mouse
Bovine
Rat
Human
Uniprot Human
Human
Human
Human
Human
Human
Mouse
Bovine
Product By Gene ID 3565
Alternate Names
  • B cell growth factor 1
  • B-cell stimulatory factor 1
  • BCGF1
  • BCGF-1
  • binetrakin
  • Binetrakin
  • BSF1
  • BSF-1
  • IL-4B_cell stimulatory factor 1
  • interleukin 4
  • interleukin-4
  • Lymphocyte stimulatory factor 1
  • MGC79402
  • Pitrakinra
  • pitrakinra

Research Areas for IL-4

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Asthma
Biologically Active Proteins
Cancer
Cytokine Research
Immunology
Innate Immunity

Related IL-4 Blog Posts

Check out the latest blog posts on IL-4.
Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...    Read more.
Read more IL-4 related blogs.