IL-18/IL-1F4 Antibody (S02-8B2)

Immunohistochemistry-Paraffin: IL-18/IL-1F4 Antibody (S02-8B2) [NBP3-20042] - Immunohistochemistry of IL-18/IL-1F4 in paraffin-embedded Human colon cancer tissue using NBP3-20042 at dilution 1/50

Western Blot: IL-18/IL-1F4 Antibody (S02-8B2) [NBP3-20042] - Western blot detection of IL-18/IL-1F4 in Hela cell lysates using NBP3-20042 (1:1000 diluted). Predicted band size: 22kDa. Observed band size: 17kDa.

• Reactivity: Hu
• Applications: WB, IHC
• Clone: S02-8B2
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.3 mg/ml

IL-18/IL-1F4 Antibody (S02-8B2) Summary

• Description: Novus Biologicals Rabbit IL-18/IL-1F4 Antibody (S02-8B2) (NBP3-20042) is a recombinant monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant protein of human IL-18/IL-1F4 (Uniprot # Q14116)
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: IL18
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1/200
  • Immunohistochemistry-Paraffin
  • Western Blot 1/1000
• Theoretical MW: 17 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Concentration: 0.3 mg/ml
• Purity: Affinity purified

Alternate Names for IL-18/IL-1F4 Antibody (S02-8B2)

• Iboctadekin
• IFN-gamma-inducing factor
• IGIF
• IGIFIL-1 gamma
• IL18
• IL-18
• IL-18MGC12320
• IL-1F4
• IL1F4iboctadekin
• IL-1g
• Interferon gamma-inducing factor
• interleukin 18 (interferon-gamma-inducing factor)
• Interleukin-1 gamma
• interleukin-18

Background

The protein encoded by the IL18 gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL18