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IL-18/IL-1F4 Products

Antibodies
IL-18/IL-1F4 Antibody [Unconj ...
IL-18/IL-1F4 Antibody [Unconjugated]
AF2548
HAF017). A specific band was detected for IL-18/IL-1F4 at approximately 22 kDa (as indicated). GAPDH (Catalog # AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
NL001) and counterstained with DAPI (green). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells." class="big_lightbox" target="_blank"> Immunocytochemistry IL-18/IL-1F4 Antibody [Unconjugated]
HAF109). This experiment was conducted under reducing conditions and using the 2-40. kDa separation system." class="big_lightbox" target="_blank"> Simple Western IL-18/IL-1F4 Antibody [Unconjugated]
210-TA), Recombinant Rhesus Macaque IL-18/IL-1F4 (Catalog # 2548-RM) stimulates IFN-gamma secretion in the KG-1 human acute myelogenous leukemia cell line in a dose-dependent manner (orange line), as measured by the Human IFN-gamma Quantikine ELISA Kit (Catalog # DIF50C). Under these conditions, IFN-gamma secretion elicited by Recombinant Rhesus Macaque IL-18/IL-1F4 (10 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human/Rhesus Macaque IL-18/IL-1F4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2548). The ND50 is typically 0.4-1.2 µg/mL." class="big_lightbox" target="_blank"> Neutralization IL-18/IL-1F4 Antibody [Unconjugated]
HAF017). A specific band was detected for IL-18/IL-1F4 at approximately 25 kDa (as indicated) in the parental HeLa cell line, but is not detectable in knockout HeLa cell line. GAPDH (Catalog # AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Knockout Validated IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Western Blot IL-18/IL-1F4 Antibody [Unconjugated]
Species: Hu, RM
Applications: WB, Simple Western, ELISA, B/N, ICC/IF, KO
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 AF2548U-100UG
Alexa Fluor 405 AF2548V-100UG
Alexa Fluor 488 AF2548G-100UG
Alexa Fluor 532 AF2548X-100UG
Alexa Fluor 594 AF2548T-100UG
Alexa Fluor 647 AF2548R-100UG
Alexa Fluor 700 AF2548N-100UG
Alexa Fluor 750 AF2548S-100UG
Alexa Fluor Plus 405 AF2548AFP405-100UG
Alexa Fluor Plus 488 AF2548AFP488-100UG
Alexa Fluor Plus 555 AF2548AFP555-100UG
Alexa Fluor Plus 594 AF2548AFP594-100UG
Alexa Fluor Plus 647 AF2548AFP647-100UG
Alexa Fluor Plus 680 AF2548AFP680-100UG
Allophycocyanin AF2548A
Biotin AF2548B
CoraFluor 1 AF2548CL1
DyLight 350 AF2548D
DyLight 405 AF2548E
DyLight 488 AF2548K
DyLight 550 AF2548L
DyLight 594 AF2548M
DyLight 650 AF2548W
DyLight 680 AF2548Y
DyLight 755 AF2548Z
FITC AF2548F
HRP AF2548H
Janelia Fluor 525 AF2548JF525
Janelia Fluor 549 AF2548I
Janelia Fluor 646 AF2548J
Janelia Fluor 669 AF2548JF669
PE AF2548P
PerCP AF2548C
mFluor Violet 450 SE AF2548MFV450
mFluor Violet 500 SE AF2548MFV500
mFluor Violet 610 SE AF2548MFV610
Formulation Catalog # Availability Price  
Carrier Free AF2548-SP
IL-18/IL-1F4 Antibody
IL-18/IL-1F4 Antibody
AF521
419-ML), Recombinant Rat IL-18/IL-1F4 (Catalog # 521-RL) stimulates IFN-gamma secretion in activated mouse T cells in a dose-dependent manner (orange line), as measured by the Mouse IFN-gamma Quantikine ELISA Kit (Catalog # MIF00). Under these conditions, IFN-gamma secretion elicited by Recombinant Rat IL-18/IL-1F4 (15 ng/mL) is neutralized (green line) by increasing concentrations of Rat IL-18/IL-1F4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF521). The ND50 is typically 1-3 µg/mL." class="big_lightbox" target="_blank"> Neutralization IL-18/IL-1F4 Antibody
Western Blot IL-18/IL-1F4 Antibody
Western Blot IL-18/IL-1F4 Antibody
Western Blot IL-18/IL-1F4 Antibody
Western Blot IL-18/IL-1F4 Antibody
Species: Rt
Applications: WB, B/N
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 AF521U-100UG
Alexa Fluor 405 AF521V-100UG
Alexa Fluor 488 AF521G-100UG
Alexa Fluor 532 AF521X-100UG
Alexa Fluor 594 AF521T-100UG
Alexa Fluor 647 AF521R-100UG
Alexa Fluor 700 AF521N-100UG
Alexa Fluor 750 AF521S-100UG
Alexa Fluor Plus 405 AF521AFP405-100UG
Alexa Fluor Plus 488 AF521AFP488-100UG
Alexa Fluor Plus 555 AF521AFP555-100UG
Alexa Fluor Plus 594 AF521AFP594-100UG
Alexa Fluor Plus 647 AF521AFP647-100UG
Alexa Fluor Plus 680 AF521AFP680-100UG
Allophycocyanin AF521A
Biotin BAF521
CoraFluor 1 AF521CL1
DyLight 350 AF521D
DyLight 405 AF521E
DyLight 488 AF521K
DyLight 550 AF521L
DyLight 594 AF521M
DyLight 650 AF521W
DyLight 680 AF521Y
DyLight 755 AF521Z
FITC AF521F
HRP AF521H
Janelia Fluor 525 AF521JF525
Janelia Fluor 549 AF521I
Janelia Fluor 646 AF521J
Janelia Fluor 669 AF521JF669
PE AF521P
PerCP AF521C
mFluor Violet 450 SE AF521MFV450
mFluor Violet 500 SE AF521MFV500
mFluor Violet 610 SE AF521MFV610
Formulation Catalog # Availability Price  
Carrier Free AF521-SP
IL-18/IL-1F4 Antibody (25-2G) ...
IL-18/IL-1F4 Antibody (25-2G) [Unc...
D043-3
Species: Hu
Applications: WB
Host: Mouse Monoclonal
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We have 95 IL-18/IL-1F4 Antibodies
Antibody Pairs
IL-18/IL-1F4 Antibody Pair [H ...
IL-18/IL-1F4 Antibody Pair [HRP]
NBP2-79447
Sandwich ELISA IL-18/IL-1F4 Antibody Pair [HRP]
Species: Hu
Applications: ELISA
Host: Rabbit
Conjugate Catalog # Availability Size Price
HRP NBP2-79447-5Plates
HRP NBP2-79447-15Plates
IL-18/IL-1F4 Antibody Pair [H ...
IL-18/IL-1F4 Antibody Pair [HRP]
NBP2-79493
Sandwich ELISA IL-18/IL-1F4 Antibody Pair [HRP]
Species: Mu
Applications: ELISA
Host: Rabbit Monoclonal
Conjugate Catalog # Availability Size Price
HRP NBP2-79493-5Plates
HRP NBP2-79493-15Plates
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We have 2 IL-18/IL-1F4 Antibody Pairs
ELISA Kits
Human Total IL-18/IL-1F4 Quan ...
Human Total IL-18/IL-1F4 Quantikin...
DL180
N/A IL-18/IL-1F4 [HRP]
N/A IL-18/IL-1F4 [HRP]
N/A IL-18/IL-1F4 [HRP]
Species: Hu
Applications: ELISA
Mouse IL-18/IL-1F4 ELISA
Mouse IL-18/IL-1F4 ELISA
7625
Species: Mu
Applications: ELISA
Human Total IL-18 DuoSet ELIS ...
Human Total IL-18 DuoSet ELISA, 5 ...
DY318-05
N/A IL-18/IL-1F4 [Biotin]
Species: Hu
Applications: ELISA
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We have 21 IL-18/IL-1F4 ELISA Kits
Lysates
IL-18/IL-1F4 Overexpression L ...
IL-18/IL-1F4 Overexpression Lysate
NBP2-04199
Western Blot IL-18/IL-1F4 Overexpression Lysate
Species: Hu
Applications: WB
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We have 1 IL-18/IL-1F4 Lysate
Proteins
Recombinant Mouse IL-18/IL-1F ...
Recombinant Mouse IL-18/IL-1F4 Pro...
9139-IL
Bioactivity IL-18/IL-1F4 [Unconjugated]
SDS-Page IL-18/IL-1F4 [Unconjugated]
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Carrier Free 9139-IL-050/CF
Carrier Free 9139-IL-010/CF
Carrier Free 9139-IL-500/CF
Recombinant Human IL-18/IL-1F ...
Recombinant Human IL-18/IL-1F4 Pro...
9124-IL
SEC-MALS IL-18/IL-1F4 [Unconjugated]
Bioactivity IL-18/IL-1F4 [Unconjugated]
SDS-Page IL-18/IL-1F4 [Unconjugated]
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Carrier Free 9124-IL-050/CF
Carrier Free 9124-IL-500/CF
Carrier Free 9124-IL-010/CF
Recombinant Rat IL-18/IL-1F4 ...
Recombinant Rat IL-18/IL-1F4 Protein
521-RL
Species: Rt
Applications: Bioactivity
Formulation Catalog # Availability Price  
Carrier Free 521-RL-025/CF
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We have 10 IL-18/IL-1F4 Proteins

Description

The protein encoded by the IL18 gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. (provided by RefSeq)

Bioinformatics

Entrez
16173
Mouse
29197
Rat
3606
Human
Uniprot
NP_001553
Human
NP_032386
Mouse
Q14116
Human
Product By Gene ID 3606
Alternate Names
  • Iboctadekin
  • IFN-gamma-inducing factor
  • IGIFIL-1 gamma
  • IL-18MGC12320
  • IL1F4iboctadekin
  • IL-1g
  • Interferon gamma-inducing factor
  • interleukin 18 (interferon-gamma-inducing factor)
  • Interleukin-1 gamma
  • interleukin-18

Related IL-18/IL-1F4 Blog Posts

Check out the latest blog posts on IL-18/IL-1F4.
Pyroptosis: Mechanisms mediating cell death and pro-inflammatory cytokine release
By Victoria OsinskiPyroptosis is an inflammatory form of programmed cell death characterized by the release of pro-inflammatory cytokines IL-1 beta and IL-18.1,10 It is a process distinct from apoptosis and necrosis (T...    Read more.
Immune Cell Metabolic Flux Influences Type I Diabetes
By Hunter MartinezWhat is Immunometabolism?It is well established that abnormal metabolic environments can be a risk factor for disease development. One characteristic example is the role of dyslipidemia (high lev...    Read more.
Read more IL-18/IL-1F4 related blogs.