IL-17E/IL-25 Antibody (68C1039.2) - Azide and BSA Free

Western Blot: IL-17E/IL-25 Antibody (68C1039.2) - Azide Free [NBP2-33223] - Analysis of IL-17E using IL-17E monoclonal antibody. Mouse testis lysate probed with IL-17E antibody at 2 ug/mL. Image from the standard format of this antibody.

Immunohistochemistry: IL-17E/IL-25 Antibody (68C1039.2) - Azide Free [NBP2-33223] - Tissue section of mouse kidney using IL17E/IL25 antibody clone 68C1039.2 at 1:150. The antibody generated a diffused cytoplasmic staining in the tubular and ductal epithelia cells, and a strong positivity in the inter-tubular/ductal blood vessels. Image f

Immunohistochemistry: IL-17E/IL-25 Antibody (68C1039.2) - Azide Free [NBP2-33223] - Adrenal cortex, Human Image from the standard format of this antibody.

Immunohistochemistry: IL-17E/IL-25 Antibody (68C1039.2) - Azide Free [NBP2-33223] - Tissue section of mouse liver using IL17E/IL25 antibody clone 68C1039.2 at 1:150. The antibody generated a diffused cytoplasmic staining in the hepatocytes with a very strong signal in the sinusoidal endothelial cells. Image from the standard format of th

• Reactivity: Hu, Mu
• Applications: WB, IHC
• Clone: 68C1039.2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1.0 mg/ml

IL-17E/IL-25 Antibody (68C1039.2) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse IL-17E/IL-25 Antibody (68C1039.2) - Azide and BSA Free (NB100-56541) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Amino acids 115-132 of human IL-17E (isoform CRA_a) were used as immunogen for this antibody.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL25
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20-1:1000
  • Immunohistochemistry-Paraffin 1:10-1:500. Use reported in scientific literature (Terrier B et al)
  • Western Blot 2-4 ug/ml
• Application Notes: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Theoretical MW: 20 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for IL-17E/IL-25 Antibody (68C1039.2) - Azide and BSA Free

• IL17E
• IL-17E
• IL25
• IL-25
• interleukin 25
• Interleukin-17E
• interleukin-25

Background

Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E (2). IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis (3), multiple sclerosis (4), and promotion of tumor growth (5). IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated by Shi, et al (6) and Lee, et al. (2) and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL25