IL-17E/IL-25 Products

Description

Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E (2). IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis (3), multiple sclerosis (4), and promotion of tumor growth (5). IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated by Shi, et al (6) and Lee, et al. (2) and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8.

Bioinformatics

Entrez	140806 Mouse 64806 Human
Uniprot	NM_022789 Human NP_073626 Human NP_073626.1 Human NP_542767 Mouse Q9H293 Human
Product By Gene ID	64806
Alternate Names	IL17E IL-17E IL-25 interleukin 25 Interleukin-17E interleukin-25

Research Areas for IL-17E/IL-25

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research