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MAB002, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2Secondary Antibody (Catalog # F0101B). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin." class="big_lightbox" target="_blank">
1399-IL) was serially diluted and captured by Rat Anti-Mouse IL‑17E/IL‑25 Monoclonal Antibody (Catalog # MAB13991) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Mouse IL‑17E/IL‑25 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1399) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E (2). IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis (3), multiple sclerosis (4), and promotion of tumor growth (5). IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated by Shi, et al (6) and Lee, et al. (2) and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8.
![N/A IL-17E/IL-25 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_IL17E_DY1399_ELISA_1641.jpg)
![N/A IL-17E/IL-25 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_IL17E_DY125805_ELISA_2347.jpg)
![Bioactivity IL-17E/IL-25 [Unconjugated]](http://images.novusbio.com/fullsize/protein/IL17E_8134IL_1009.jpg)
![Intracellular Staining by Flow Cytometry IL-17E/IL-25 Antibody (182203) [Unconjugated]](http://images.novusbio.com/images/antibody/IL-17E_MAB1258_Flow_Cytometry_8332.jpg)
![Immunocytochemistry/ Immunofluorescence IL-17E/IL-25 Antibody (182203) [Unconjugated]](http://images.novusbio.com/fullsize/mab1258_human-il-17e-il-25-mab-clone-182203-41202412505384.jpg)
![Immunocytochemistry/ Immunofluorescence IL-17E/IL-25 Antibody (182203) [Unconjugated]](http://images.novusbio.com/fullsize/mab1258_human-il-17e-il-25-mab-clone-182203-41202412514883.jpg)
![Immunocytochemistry/ Immunofluorescence IL-17E/IL-25 Antibody (182203) [Unconjugated]](http://images.novusbio.com/fullsize/mab1258_human-il-17e-il-25-mab-clone-182203-41202412521123.jpg)
![Immunocytochemistry/ Immunofluorescence IL-17E/IL-25 Antibody (182203) [Unconjugated]](http://images.novusbio.com/fullsize/mab1258_human-il-17e-il-25-mab-clone-182203-41202412513830.jpg)
![Immunocytochemistry/ Immunofluorescence IL-17E/IL-25 Antibody (182203) [Unconjugated]](http://images.novusbio.com/fullsize/mab1258_human-il-17e-il-25-mab-clone-182203-4120241251481.jpg)
![SDS-Page IL-17E/IL-25 [Unconjugated]](http://images.novusbio.com/fullsize/protein/IL17E_8134IL_1352.jpg)
