Recombinant Human IFN-gamma Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-99309
    • Availability
      Product Discontinued

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Recombinant Human IFN-gamma Protein Summary

Description
Recombinant bioactive protein containing 144 amino acids for Human IFN-gamma

Source:E. coli
Amino Acid Sequence:(P01579)

Preparation
Method
Determined to be >98% pure by SDS-PAGE
Details of Functionality
The ED50 as determined in a viral resistance assay is < 0.05 ng/ml, corresponding to a specific activity of > 2 x 107 units/mg.
Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
IFNG
Purity
>98%, by SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Applications/Dilutions

Dilutions
  • Bioactivity
  • SDS-Page
Theoretical MW
16.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
Lyophilized.
Concentration
Lyoph
Purity
>98%, by SDS-PAGE
Reconstitution Instructions
Reconstitute in dH2O to 0.1 - 1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4C for 1 week or -20C for long-term storage.

Alternate Names for Recombinant Human IFN-gamma Protein

  • IFG
  • IFI
  • IFNG
  • IFNgamma
  • IFN-gamma
  • Immune interferon
  • interferon gamma
  • interferon, gamma

Background

IFN-gamma is a lymphoid factor that possesses potent anti-viral activity. It has also been shown that INF-g stimulates microphages and NK cells. Recombinant human IFN-gamma is a 16.9 kDa protein containing 144 amino acid residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for IFN-gamma Protein (NBP1-99309) (0)

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FAQs for IFN-gamma Protein (NBP1-99309). (Showing 1 - 1 of 1 FAQ).

  1. Is Recombinant Human IFN-gamma Protein - Clinical grade or preclinical ?
    • We are research use only.

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Research Areas for IFN-gamma Protein (NBP1-99309)

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Blogs on IFN-gamma.

Tired T cells: Hypoxia Drives T cell Exhaustion in the Tumor Microenvironment
By Hunter MartinezThe paradigm shifting view of the immune system being leveraged to target cancer has led to numerous therapeutic breakthroughs. One major cell group responsible for this revelation is a T cell. ...  Read full blog post.

Early T cell response is associated with mild COVID-19 and rapid SARS-CoV-2 clearance
Jamshed Arslan, Pharm D, PhD SARS-CoV-2 induces both humoral and cellular immunity. A vaccine or natural infection invokes SARS-CoV-2-specific humoral components (antibodies from activated B cells) and cellular resp...  Read full blog post.


  Read full blog post.

Success of combined IL-10 and IL-12 therapy in colon cancer depends on IFN-gamma and gut barrier integrity
By Jamshed Arslan, Pharm. D., PhD. Colon cancer is responsible for over 600,000 deaths per year worldwide. Colon cancer can be classified into two categories: mismatch repair (MMR)-deficient and MMR-proficient cancers...  Read full blog post.

You complete me: Natural killer cells need TGF-beta inhibition to effectively combat cancers
By Jamshed Arslan Pharm.D. Natural killer (NK) cells are lymphocytes of the innate immune system that were first discovered for their “natural” ability to kill cancer cells. To use NK cells as anti-cancer therapy, t...  Read full blog post.

iNOS: The Nitric Oxide Boss
Nitric oxide (NO) is an inorganic, gaseous, and reactive free radical that acts as a biologic mediator in processes such as neurotransmission, vasorelaxation, and cytotoxicity. In addition, it has antimicrobial and anti-tumoral activities. NO producti...  Read full blog post.

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Bioinformatics

Gene Symbol IFNG