IFN-gamma Antibody (4S.B3)

Product Discontinued

IFN-gamma Antibody (4S.B3) Summary

• Immunogen: This antibody was generated by immunizing host with Partially purified, native human IFN-γ
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: IFNG
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Each lot of this antibody is quality control tested by ELISA assay. For ELISA Capture applications, the antibody should be titrated between 0.25 - 2 µg/ml to determine optimal condition. It is recommended that the reagent be titrated for optimal performance for each application. Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID: 28979689).

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 28979689). Cross-Reactivity Chimpanzee, Baboon, Cynomolgus, Rhesus

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.2)
• Preservative: 0.09% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A or G purified

Alternate Names for IFN-gamma Antibody (4S.B3)

• IFG
• IFI
• IFNG
• IFNgamma
• IFN-gamma
• Immune interferon
• interferon gamma
• interferon, gamma

Background

Interferon-gamma is a potent multifunctional cytokine which is secreted primarily by activated NK cells and T cells. Originally characterized based on anti-viral activities, IFN-gamma also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-gamma can upregulate MHC class I and II antigen expression by antigen-presenting cells. The 4S.B3 antibody reacts with the human IFN-gamma. The 4S.B3 antibody can neutralize the bioactivity of natural or recombinant IFN-gamma. The 4S.B3 antibody cross reacts with monkey IFN-gamma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for IFN-gamma Antibody (NBP1-49013)(1)

Publication using NBP1-49013

• Cheng W, Su J, Hu Y et al. Interleukin-25 primed mesenchymal stem cells achieve better therapeutic effects on dextran sulfate sodium-induced colitis via inhibiting Th17 immune response and inducing T regulatory cell phenotype. Am J Transl Res 2017-09-15 [PMID: 28979689] (ICC/IF, Rat)

FAQs for IFN-gamma Antibody (NBP1-49013). (Showing 1 - 1 of 1 FAQ).

1. Is Recombinant Human IFN-gamma Protein - Clinical grade or preclinical ?
   • We are research use only.

Bioinformatics

• Gene Symbol: IFNG