ICAT/CTNNBIP1 Antibody (SR1112) - BSA Free

Western Blot: ICAT/CTNNBIP1 Antibody (SR1112) [NBP3-22453] - Western blot analysis using NBP3-22453 in 293T cell lysate.

• Reactivity: Hu
• Applications: WB, Flow, IP
• Clone: SR1112
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ICAT/CTNNBIP1 Antibody (SR1112) - BSA Free Summary

• Description: Novus Biologicals Rabbit ICAT/CTNNBIP1 Antibody (SR1112) - BSA Free (NBP3-22453) is a recombinant monoclonal antibody validated for use in WB, Flow and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human ICAT/CTNNBIP1 (Uniprot #: Q9NSA3)
• Specificity: Detects endogenous levels of total ICAT/CTNNBIP1
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: CTNNBIP1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:50
  • Immunoprecipitation 1:50
  • Western Blot 1:500-1:2000
• Theoretical MW: 12 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ICAT/CTNNBIP1 Antibody (SR1112) - BSA Free

• beta-catenin-interacting protein ICAT
• catenin, beta interacting protein 1
• CTNNBIP1
• ICAT
• ICATbeta-interacting protein 1
• Inhibitor of beta-catenin and Tcf-4

Background

CTNNBIP1, or Beta-catenin-interacting protein 1, consists of a short 81 amino acid isoform that is approximately 9 kDa, and is involved in the negative regulation of the Wnt signaling pathway, and it also prevents CTNNB1 and TCF from interacting. Current research is being conducted on CTNNBIP1 and a number of diseases to determine the relationship between the two. Some of these disorders and diseases include: actinic cheilitis, nasopharyngitis, adenomatous polyposis coli, gastric cancer, cheilitis, esophagitis, esophageal squamous cell carcinoma, laryngitis, desmoid tumor, hepatocellular carcinoma, acute lymphoblastic leukemia, medulloblastoma, malignant glioma, duodenitis, wilms tumor, endometrial carcinoma, and polyposis. CTNNBIP1 is linked to the Wnt signaling pathway, where it interacts with JUP, CTNNB1, BEND5, CASP4, and CPVL.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CTNNBIP1