ICAT/CTNNBIP1 Products

Description

CTNNBIP1, or Beta-catenin-interacting protein 1, consists of a short 81 amino acid isoform that is approximately 9 kDa, and is involved in the negative regulation of the Wnt signaling pathway, and it also prevents CTNNB1 and TCF from interacting. Current research is being conducted on CTNNBIP1 and a number of diseases to determine the relationship between the two. Some of these disorders and diseases include: actinic cheilitis, nasopharyngitis, adenomatous polyposis coli, gastric cancer, cheilitis, esophagitis, esophageal squamous cell carcinoma, laryngitis, desmoid tumor, hepatocellular carcinoma, acute lymphoblastic leukemia, medulloblastoma, malignant glioma, duodenitis, wilms tumor, endometrial carcinoma, and polyposis. CTNNBIP1 is linked to the Wnt signaling pathway, where it interacts with JUP, CTNNB1, BEND5, CASP4, and CPVL.

Bioinformatics

Entrez	56998 Human
Uniprot	NP_001012329 Human NP_064633 Human P35222 Human
Product By Gene ID	56998
Alternate Names	beta-catenin-interacting protein ICAT catenin, beta interacting protein 1 ICATbeta-interacting protein 1 Inhibitor of beta-catenin and Tcf-4

Research Areas for ICAT/CTNNBIP1

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Signal Transduction
Wnt Signaling Pathway