HYPE Antibody (OTI2A11) [DyLight 755]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI2A11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 755

HYPE Antibody (OTI2A11) [DyLight 755] Summary

• Immunogen: Recombinant protein fragment corresponding to amino acids 61-265 of human HYPE (NP_009007) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FICD
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for HYPE Antibody (OTI2A11) [DyLight 755]

• AMPylator FICD
• EC 2.7.7.n1
• FIC domain containing
• FIC domain-containing protein
• fic S-phase protein cell division homolog
• HIP-13
• HIP13UNQ3041
• huntingtin interacting protein 13
• Huntingtin interacting protein E
• huntingtin interactor protein E
• Huntingtin yeast partner E
• Huntingtin-interacting protein 13
• Huntingtin-interacting protein E
• HYPEadenosine monophosphate-protein transferase FICD
• MGC5623

Background

Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FICD