HYPE Products

Description

Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified

Bioinformatics

Entrez	11153 Human
Uniprot	AAH01342 Human NM_007076 Human NP_009007 Human NP_009007.2 Human Q9BVA6 Human
Product By Gene ID	11153
Alternate Names	AMPylator FICD EC 2.7.7.n1 FIC domain containing FIC domain-containing protein fic S-phase protein cell division homolog HIP-13 HIP13UNQ3041 huntingtin interacting protein 13 Huntingtin interacting protein E huntingtin interactor protein E Huntingtin yeast partner E Huntingtin-interacting protein 13 Huntingtin-interacting protein E HYPEadenosine monophosphate-protein transferase FICD MGC5623

Research Areas for HYPE

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Cell Cycle and Replication