Human S100B DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human S100B DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: S100B

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human S100B DuoSet ELISA, 5 Plate

• beta (neural)
• NEF
• S100 beta
• S100 calcium binding protein B
• S100 calcium-binding protein B
• S100 calcium-binding protein, beta (neural)
• S-100 calcium-binding protein, beta chain, 10protein S100-B
• S-100 protein beta chain
• S-100 protein subunit beta
• S100
• S100B
• S100beta

Background

S100B belongs to the S100 subgroup of the EF-hand family of calcium binding proteins. It is a homodimer that is expressed primarily in the brain by astrocytes, oligodendrocytes and Schwann cells. S100B has multiple intracellular functions, but can also be secreted from cells to exert extracellular functions. Some of the extracellular functions of S100B may be mediated by RAGE (receptor for advanced glycation end products). Blood levels of S100B can be used to monitor the extent of brain injury and malignant melanoma.

Publications for S100B (DY1820-05)(15)

Publications using DY1820-05

• Hindman, BJ;Olinger, CR;Woodroffe, RW;Zanaty, M;Streese, CD;Zacharias, ZR;Houtman, JCD;Wendt, LH;Ten Eyck, PP;O'Connell-Moore, DJ;Ray, EJ;Lee, SJ;Waldschmidt, DF;Havertape, LG;Nguyen, LB;Chen, PF;Banks, MI;Sanders, RD;Howard, MA; Exploratory Randomised Trial of Tranexamic Acid to Decrease Postoperative Delirium in Adults Undergoing Lumbar Fusion: A trial stopped early medRxiv : the preprint server for health sciences 2024-10-17 [PMID: 39484259] (Human)
• Cherpaz, M;Meugnier, E;Seillier, G;Pozzi, M;Pierrard, R;Leboube, S;Farhat, F;Vola, M;Obadia, JF;Amaz, C;Chalabreysse, L;May, C;Chanon, S;Brun, C;Givre, L;Bidaux, G;Mewton, N;Derumeaux, G;Bergerot, C;Paillard, M;Thibault, H; Myocardial transcriptomic analysis of diabetic patients with aortic stenosis: key role for mitochondrial calcium signaling Cardiovascular diabetology 2024-07-08 [PMID: 38978010] (Human)
• Tsoporis, JN;Triantafyllis, AS;Kalogeropoulos, AS;Izhar, S;Rigopoulos, AG;Rallidis, LS;Sakadakis, E;Toumpoulis, IK;Salpeas, V;Leong-Poi, H;Parker, TG;Rizos, I; Differential Expression of Circulating Damage-Associated Molecular Patterns in Patients with Coronary Artery Ectasia Biomolecules 2023-12-21 [PMID: 38275751] (Human)
• de Sousa, DC;Sobreira, EST;Feitosa, WLQ;Aires, TMPM;Araújo, LPP;Silva, ALC;Joventino, CB;Silveira, NMT;Chaves-Filho, AJM;Macêdo, DS;Braga-Neto, P; Cognitive dysfunction in systemic lupus erythematosus is associated with disease activity and oxidative stress: a comparative study with rheumatoid arthritis for identifying biomarkers BMC neuroscience 2023-12-13 [PMID: 38093175] (Human)
• Levchuk, LA;Roschina, OV;Mikhalitskaya, EV;Epimakhova, EV;Simutkin, GG;Bokhan, NA;Ivanova, SA; Serum Levels of S100B Protein and Myelin Basic Protein as a Potential Biomarkers of Recurrent Depressive Disorders Journal of personalized medicine 2023-09-21 [PMID: 37763190] (Human)
• SD Sharma, BK Reddy, R Pal, TE Ritakari, JD Cooper, BT Selvaraj, PC Kind, S Chandran, DJA Wyllie, S Chattarji Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons Cell Reports, 2023-04-04;42(4):112344. 2023-04-04 [PMID: 37018073] (Human)
• SY Cho, HT Roh Effects of Exercise Training on Neurotrophic Factors and Blood-Brain Barrier Permeability in Young-Old and Old-Old Women International Journal of Environmental Research and Public Health, 2022-12-16;19(24):. 2022-12-16 [PMID: 36554777] (Human)
• HT Sherman, K Liu, K Kwong, ST Chan, AC Li, XJ Kong Carbon monoxide (CO) correlates with symptom severity, autoimmunity, and responses to probiotics treatment in a cohort of children with autism spectrum disorder (ASD): a post-hoc analysis of a randomized controlled trial BMC Psychiatry, 2022-08-08;22(1):536. 2022-08-08 [PMID: 35941573] (Human)
• W Zwoli?ska, M Skibinska, A S?opie?, M Dmitrzak-W ProBDNF as an Indicator of Improvement among Women with Depressive Episodes Metabolites, 2022-04-16;12(4):. 2022-04-16 [PMID: 35448545] (Human)
• A Rajewska-R, M Dmitrzak-W, P Kapelski, N Lepczynska, J Pawlak, J Twarowska-, M Skibinska Longitudinal assessment of S100B serum levels and clinical factors in youth patients with mood disorders Scientific Reports, 2021-06-07;11(1):11973. 2021-06-07 [PMID: 34099858] (Human)
• JN Tsoporis, E Hatziagela, S Gupta, S Izhar, V Salpeas, A Tsiavou, AG Rigopoulos, AS Triantafyl, JC Marshall, TG Parker, IK Rizos Circulating Ligands of the Receptor for Advanced Glycation End Products and the Soluble Form of the Receptor Modulate Cardiovascular Cell Apoptosis in Diabetes Molecules, 2020-11-10;25(22):. 2020-11-10 [PMID: 33182705] (Human)
• CR Schindler, T Lustenberg, M Woschek, P Störmann, D Henrich, P Radermache, I Marzi Severe Traumatic Brain Injury (TBI) Modulates the Kinetic Profile of the Inflammatory Response of Markers for Neuronal Damage J Clin Med, 2020-06-01;9(6):. 2020-06-01 [PMID: 32492963] (Human)
• R Tao, Z Fu, L Xiao Chronic Food Antigen-specific IgG-mediated Hypersensitivity Reaction as A Risk Factor for Adolescent Depressive Disorder Genomics Proteomics Bioinformatics, 2019-06-21;0(0):. 2019-06-21 [PMID: 31233833] (Human)
• X Liu, X Jin, B Chen, X Liu, X Liang, X Fang, H Wu, X Fu, H Zheng, X Ding, N Duan, Y Zhang Effects of Kudiezi Injection on Serum Inflammatory Biomarkers in Patients with Acute Cerebral Infarction Dis. Markers, 2018-09-02;2018(0):7936736. 2018-09-02 [PMID: 30245755] (Human)
• Yunlong Tan Cognitive dysfunction correlates with elevated serum S100B concentration in drug-free acutely relapsed patients with schizophrenia Psychiatry Res, 2016-09-22;247(0):6-11. 2016-09-22 [PMID: 27863321] (Human)

FAQs for S100B (DY1820-05). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: S100B