Human IL-23 Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human IL-23 Quantikine ELISA Kit Summary

Background
The Quantikine Human IL-23 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human IL-23 in cell culture supernates, serum, and plasma. It contains Sf 21-expressed recombinant human IL-23 and has been shown to accurately quantitate the recombinant factor. Results obtained for naturally occurring human IL-23 showed linear curves that were parallel to the standard curves... obtained using the kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human IL-23.
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Specificity
Natural and recombinant human IL-23. This assay does not recognize free p19 or p40 subunits.
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
IL23A

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using D2300B.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-23 Quantikine ELISA Kit

  • IL-23 p19/IL-12 p40
  • IL23
  • IL-23
  • IL-23A
  • IL-23-A
  • IL-23p19
  • IL-23p19/IL-12p40
  • IL23P19P19
  • interleukin 23 p19 subunit
  • interleukin 23, alpha subunit p19
  • interleukin-23 subunit alpha
  • Interleukin-23 subunit p19
  • JKA3 induced upon T-cell activation
  • MGC79388
  • SGRF
  • SGRFIL-23 subunit alpha

Background

IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for IL-23A/IL-23 P19 (D2300B)(18)

We have publications tested in 1 confirmed species: Human.


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Human
(18)
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Showing Publications 1 - 10 of 18. Show All 18 Publications.
Publications using D2300B Applications Species
MM Abhyankar, JZ Ma, KW Scully, AJ Nafziger, AL Frisbee, MM Saleh, GR Madden, AR Hays, M Poulter, WA Petri Immune Profiling To Predict Outcome of Clostridioides difficile Infection MBio, 2020;11(3):. 2020 [PMID: 32457246] (Human) Human
H Yu, S Cui, Y Mei, Q Li, L Wu, S Duan, G Cai, H Zhu, B Fu, L Zhang, Z Feng, X Chen Mesangial Cells Exhibit Features of Antigen-Presenting Cells and Activate CD4+ T Cell Responses J Immunol Res, 2019;2019(0):2121849. 2019 [PMID: 31317046] (Human) Human
S Clayton, E Cauble, A Kumar, N Patil, D Ledford, N Kolliputi, MF Lopes-Vire, D Castell, J Richter Plasma levels of TNF-?, IL-6, IFN-?, IL-12, IL-17, IL-22, and IL-23 in achalasia, eosinophilic esophagitis (EoE), and gastroesophageal reflux disease (GERD) BMC Gastroenterol, 2019;19(1):28. 2019 [PMID: 30744559] (Human) Human
C Guida, SD Stephen, M Watson, N Dempster, P Larraufie, T Marjot, T Cargill, L Rickers, M Pavlides, J Tomlinson, JFL Cobbold, CM Zhao, D Chen, F Gribble, F Reimann, R Gillies, B Sgromo, P Rorsman, JD Ryan, RD Ramracheya PYY plays a key role in the resolution of diabetes following bariatric surgery in humans EBioMedicine, 2019;0(0):. 2019 [PMID: 30639417] (Human) Human
N Ma, Q Tang, WT Wu, XA Huang, Q Xu, GL Rong, S Chen, JP Song Three Constituents of Moringa oleifera Seeds Regulate Expression of Th17-Relevant Cytokines and Ameliorate TPA-Induced Psoriasis-Like Skin Lesions in Mice Molecules, 2018;23(12):. 2018 [PMID: 30544700] (Human) Human
T Zheng, C Xu, C Mao, X Mou, F Wu, X Wang, L Bu, Y Zhou, X Luo, Q Lu, H Liu, G Yuan, S Wang, D Chen, Y Xiao Increased Interleukin-23 in Hashimoto's Thyroiditis Disease Induces Autophagy Suppression and Reactive Oxygen Species Accumulation Front Immunol, 2018;9(0):96. 2018 [PMID: 29434604] (Human) Human
L Srinivasan, L Kilpatrick, SS Shah, S Abbasi, MC Harris Elevations of novel cytokines in bacterial meningitis in infants PLoS ONE, 2018;13(2):e0181449. 2018 [PMID: 29394248] (Human) Human
G Schmalz, I Davarpanah, J Jäger, RF Mausberg, B Krohn-Grim, J Schmidt, R Haak, U Sack, D Ziebolz MMP-8 and TIMP-1 are associated to periodontal inflammation in patients with rheumatoid arthritis under methotrexate immunosuppression - First results of a cross-sectional study J Microbiol Immunol Infect, 2017;0(0):. 2017 [PMID: 28919284] (Human) Human
Z Meng, Y Zhang, Z Wei, P Liu, J Kang, Y Zhang, D Ma, C Ke, Y Chen, J Luo, Z Gong High serum resistin associates with intrahepatic inflammation and necrosis: an index of disease severity for patients with chronic HBV infection BMC Gastroenterol, 2017;17(1):6. 2017 [PMID: 28061755] (Human) Human
Jennifer L Liedel Effects of anticipated neonatal surgical intervention on maternal milk cytokine production J. Pediatr. Surg., 2016;0(0):. 2016 [PMID: 27836369] (Human) Human
Show All 18 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for IL-23A/IL-23 P19 (D2300B). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP D2300B
HRP D2300B
HRP D2300B

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Bioinformatics

Gene Symbol IL23A