Human IL-17A/F Heterodimer DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IL-17A/F Heterodimer DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-17A/F Heterodimer DuoSet ELISA, 15 Plate

• CTLA8
• CTLA8cytotoxic T-lymphocyte-associated serine esterase 8
• Cytotoxic T-lymphocyte-associated antigen 8
• Cytotoxic T-Lymphocyte-Associated Protein 8
• IL17
• IL-17
• IL-17A
• IL-17A/F Heterodimer
• interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
• interleukin 17A
• interleukin-17A

Background

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

Publications for IL-17A/F Heterodimer (DY5194)(8)

Publications using DY5194

• H Wang, Y Li, Z Yue, Y Liu, Q Chen, D Hu, J Han Adipose-Derived Stem Cell Exosomes Inhibit Hypertrophic Scaring Formation by Regulating Th17/Treg Cell Balance BioMed Research International, 2022-10-12;2022(0):9899135. 2022-10-12 [PMID: 36277890] (Human)
• B Jung, G Ferrer, PY Chiu, R Aslam, A Ng, F Palacios, M Wysota, M Cardillo, JE Kolitz, SL Allen, JC Barrientos, KR Rai, N Chiorazzi, B Sherry Activated CLL cells regulate IL17F producing Th17 cells in miR155 dependent and outcome specific manners JCI Insight, 2022-06-22;0(0):. 2022-06-22 [PMID: 35511436] (Human)
• A Tosi, L Nardinocch, ML Carbone, L Capriotti, E Pagani, S Mastroeni, C Fortes, F Scopelliti, C Cattani, F Passarelli, A Rosato, S D'Atri, CM Failla, A Cavani Reduced Interleukin-17-Expressing Cells in Cutaneous Melanoma Biomedicines, 2021-12-16;9(12):. 2021-12-16 [PMID: 34944746] (Human)
• N Yao, T Tretter, P Kvacskay, W Merkt, N Blank, HM Lorenz, LO Tykocinski Targeting of Janus Kinases Limits Pro-Inflammatory but Also Immunosuppressive Circuits in the Crosstalk between Synovial Fibroblasts and Lymphocytes Biomedicines, 2021-10-08;9(10):. 2021-10-08 [PMID: 34680530] (Human)
• KH Liang, MW Lai, YH Lin, YD Chu, CL Lin, WR Lin, YH Huang, TH Wang, RN Chien, TH Hu, CT Yeh Plasma interleukin-17 and alpha-fetoprotein combination effectively predicts imminent hepatocellular carcinoma occurrence in liver cirrhotic patients BMC gastroenterology, 2021-04-17;21(1):177. 2021-04-17 [PMID: 33865328] (Human)
• R Gramlich, E Aliahmadi, M Peiser In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists Int J Mol Sci, 2019-03-19;20(6):. 2019-03-19 [PMID: 30893757] (Human)
• T Haruna, S Kariya, T Fujiwara, T Higaki, S Makihara, K Kanai, R Fujiwara, S Iwasaki, Y Noguchi, K Nishizaki, M Okano Association between impaired IL-10 production following exposure to Staphylococcus aureus enterotoxin B and disease severity in eosinophilic chronic rhinosinusitis Allergol Int, 2018-03-23;0(0):. 2018-03-23 [PMID: 29580813] (Human)
• Camargo J, Bhimji A, Kumar D, Kaul R, Pavan R, Schuh A, Seftel M, Lipton J, Gupta V, Humar A, Husain S Impaired T cell responsiveness to interleukin-6 in hematological patients with invasive aspergillosis. PLoS ONE, 2015-04-02;10(4):e0123171. 2015-04-02 [PMID: 25835547] (Human)

FAQs for IL-17A/F Heterodimer (DY5194). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.