Human Galectin-9 Quantikine ELISA Kit

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP

Human Galectin-9 Quantikine ELISA Kit Summary

• Background: The Quantikine Human Galectin-9 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Galectin-9 in cell culture supernates, serum, plasma, saliva, urine, and human milk. It contains E. coli-expressed recombinant human Galectin-9 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Galectin-9 showed linear curves t...hat were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Galectin-9.
  
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• Specificity: Natural and recombinant human Galectin-9.
• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: LGALS9

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Galectin-9 Quantikine ELISA Kit

• Ecalectin
• GAL9
• gal-9
• galectin 9
• Galectin9
• Galectin-9
• HUAT
• lectin, galactoside-binding, soluble, 9
• LGALS9
• LGALS9A
• MGC117375
• MGC125973
• MGC125974
• Tumor antigen HOM-HD-21
• urate transporter/channel protein

Background

The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Galectin-9 (DGAL90)(17)

Publications using DGAL90

• Zhang, Y;Song, Y;Wang, X;Shi, M;Lin, Y;Tao, D;Han, S; An NFAT1-C3a-C3aR Positive Feedback Loop in Tumor-Associated Macrophages Promotes a Glioma Stem Cell Malignant Phenotype Cancer immunology research 2024-01-30 [PMID: 38289255] (Human)
• Pe?ech, A;Rusza?a, M;Niebrzydowska-Tatus, M;Bie?, K;Kimber-Trojnar, ?;Czuba, M;?wistowska, M;Leszczy?ska-Gorzelak, B; Do Serum Galectin-9 Levels in Women with Gestational Diabetes and Healthy Ones Differ before or after Delivery? A Pilot Study Biomolecules 2023-04-20 [PMID: 37189444] (Human)
• MA Nielsen, D Køster, AY Mehta, K Stengaard-, P Busson, P Junker, K Hørslev-Pe, ML Hetland, M Østergaard, M Hvid, H Leffler, TW Kragstrup, RD Cummings, B Deleuran Increased Galectin-9 Levels Correlate with Disease Activity in Patients with DMARD-Na�ve Rheumatoid Arthritis and Modulate the Secretion of MCP-1 and IL-6 from Synovial Fibroblasts Cells, 2023-01-15;12(2):. 2023-01-15 [PMID: 36672263] (Human)
• C Kavadichan, P Singh, S Maurya, S Tota, A Kiroubagar, D Kounassega, S Anand, VS Negi, A Aggarwal Clinical and serological association of plasma 25-hydroxyvitamin D (25(OH)D) levels in lupus and the short-term effects of oral vitamin D supplementation Arthritis Research & Therapy, 2023-01-03;25(1):2. 2023-01-03 [PMID: 36597127] (Human)
• T Reyes-Vall, I Conde-Rodr, J Serna-Vill, I Ramírez-Dí, G Pérez-Vill, G Delgado-Ló, VJ Vazquez-Za, CT Gutiérrez-, L Ávila-Jimé, A García-Car, L Martínez-A, G Santos-Lóp, J Reyes-Leyv, V Vallejo-Ru Serum Levels of Galectin-9 are Increased in Cervical Cancer Patients and are Higher in Advanced Clinical Stages OncoTargets and Therapy, 2022-10-13;15(0):1211-1220. 2022-10-13 [PMID: 36246733] (Human)
• H Matsumoto, Y Fujita, T Asano, N Matsuoka, J Temmoku, S Sato, M Yashiro-Fu, K Yokose, S Yoshida, E Suzuki, T Yago, H Watanabe, A Kawakami, K Migita Association between inflammatory cytokines and immune-checkpoint molecule in rheumatoid arthritis PLoS ONE, 2021-11-18;16(11):e0260254. 2021-11-18 [PMID: 34793561] (Human)
• J Zou, X Pei, D Xing, X Wu, S Chen LINC00261 elevation inhibits angiogenesis and cell cycle progression of pancreatic cancer cells by upregulating SCP2 via targeting FOXP3 Journal of Cellular and Molecular Medicine, 2021-09-19;0(0):. 2021-09-19 [PMID: 34541823] (Human)
• LL Eriksen, MA Nielsen, TL Laursen, B Deleuran, H Vilstrup, S Støy Early loss of T lymphocyte 4-1BB receptor expression is associated with higher short-term mortality in alcoholic hepatitis PLoS ONE, 2021-08-05;16(8):e0255574. 2021-08-05 [PMID: 34352016] (Human)
• M d'Alessand, E De Vita, L Bergantini, MA Mazzei, S di Valvaso, M Bonizzoli, A Peris, P Sestini, E Bargagli, D Bennett Galactin-1, 3 and 9: Potential biomarkers in idiopathic pulmonary fibrosis and other interstitial lung diseases Respir Physiol Neurobiol, 2020-09-11;282(0):103546. 2020-09-11 [PMID: 32920057] (Human)
• AM Seifert, C Reiche, M Heiduk, A Tannert, AC Meinecke, S Baier, J von Reness, C Kahlert, M Distler, T Welsch, C Reissfelde, DE Aust, G Miller, J Weitz, L Seifert Detection of pancreatic ductal adenocarcinoma with galectin-9 serum levels Oncogene, 2020-02-13;0(0):. 2020-02-13 [PMID: 32055023] (Human)
• X Zhang, D He, S Gao, Y Wei, L Wang Aspergillus�fumigatus enhances human NK cell activity by regulating M1 macrophage polarization Mol Med Rep, 2019-06-06;20(2):1241-1249. 2019-06-06 [PMID: 31173233] (Human)
• M Chihara, M Kurita, Y Yoshihara, A Asahina, K Yanaba Clinical Significance of Serum Galectin-9 and Soluble CD155 Levels in Patients with Systemic Sclerosis J Immunol Res, 2018-11-27;2018(0):9473243. 2018-11-27 [PMID: 30599005] (Human)
• J Gao, X Qiu, X Li, H Fan, F Zhang, T Lv, Y Song Expression profiles and clinical value of plasma exosomal Tim-3 and Galectin-9 in non-small cell lung cancer Biochem. Biophys. Res. Commun., 2018-02-13;0(0):. 2018-02-13 [PMID: 29452091] (Human)
• Z Li, X Liu, R Guo, P Wang TIM-3 plays a more important role than PD-1 in the functional impairments of cytotoxic T cells of malignant Schwannomas Tumour Biol., 2017-05-01;39(5):1010428317698. 2017-05-01 [PMID: 28475007] (Human)
• XW He, WL Li, C Li, P Liu, YG Shen, M Zhu, XP Jin Serum levels of galectin-1, galectin-3, and galectin-9 are associated with large artery atherosclerotic stroke Sci Rep, 2017-01-23;7(0):40994. 2017-01-23 [PMID: 28112232] (Human)
• Bettina Langhans Increased peripheral cd4+ regulatory t cells persist after successful direct-acting antiviral treatment of chronic hepatitis C J. Hepatol, 2016-12-29;0(0):. 2016-12-29 [PMID: 28040549] (Human)
• Mohamed Abdel-Mohs Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation PLoS Pathog, 2016-06-02;12(6):e1005677. 2016-06-02 [PMID: 27253379] (Human)

Bioinformatics

• Gene Symbol: LGALS9