Human Galectin-9 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Galectin-9 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: LGALS9

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Galectin-9 DuoSet ELISA, 15 Plate

• Ecalectin
• GAL9
• gal-9
• galectin 9
• Galectin9
• Galectin-9
• HUAT
• lectin, galactoside-binding, soluble, 9
• LGALS9
• LGALS9A
• MGC117375
• MGC125973
• MGC125974
• Tumor antigen HOM-HD-21
• urate transporter/channel protein

Background

The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities.

Publications for Galectin-9 (DY2045)(11)

Publications using DY2045

• Li, JZ;Melberg, M;Kittilson, A;Abdel-Mohsen, M;Li, Y;Aga, E;Bosch, RJ;Wonderlich, ER;Kinslow, J;Giron, LB;Di Germanio, C;Pilkinton, M;MacLaren, L;Keefer, M;Fox, L;Barr, L;Acosta, E;Ananworanich, J;Coombs, R;Mellors, J;Deeks, S;Gandhi, RT;Busch, M;Landay, A;Macatangay, B;Smith, DM;AIDS Clinical Trials Group A5345 Study Team, ; Predictors of HIV rebound differ by timing of antiretroviral therapy initiation JCI insight 2024-02-08 [PMID: 38329130] (Human)
• ST Kim, C Muñoz-Graj, SE Dunn, R Schneider, SR Johnson, Z Touma, Z Ahmad, D Bonilla, EG Atenafu, LT Hiraki, A Bookman, J Wither Interferon and interferon-induced cytokines as markers of impending clinical progression in ANA+ individuals without a systemic autoimmune rheumatic disease diagnosis Arthritis Research & Therapy, 2023-02-10;25(1):21. 2023-02-10 [PMID: 36765391] (Human)
• H Kared, AS Wolf, A Alirezayla, A Ravussin, G Solum, TT Tran, F Lund-Johan, JT Vaage, LS Nissen-Mey, UC Nygaard, O Hungnes, AH Robertson, LM Næss, L Trogstad, P Magnus, LA Munthe, S Mjaaland Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults Nature Communications, 2022-07-18;13(1):4165. 2022-07-18 [PMID: 35851055] (Human)
• L Chavez-Gal, A Ruiz, K Martinez-E, H Aguilar-Du, M Torres, R Falfan-Val, G Pérez-Rubi, M Selman, I Buendia-Ro Circulating Levels of PD-L1, TIM-3 and MMP-7 Are Promising Biomarkers to Differentiate COVID-19 Patients That Require Invasive Mechanical Ventilation Biomolecules, 2022-03-14;12(3):. 2022-03-14 [PMID: 35327637] (Human)
• S Schlichtne, NH Meyer, IM Yasinska, N Aliu, SM Berger, BF Gibbs, E Fasler-Kan, VV Sumbayev Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis International immunopharmacology, 2021-09-17;100(0):108155. 2021-09-17 [PMID: 34543981] (E. coli)
• G Dunsmore, EP Rosero, S Shahbaz, DM Santer, J Jovel, P Lacy, S Houston, S Elahi Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection PloS Biology, 2021-08-19;19(8):e3001387. 2021-08-19 [PMID: 34411088] (Human)
• N Bozorgmehr, S Mashhouri, E Perez Rose, L Xu, S Shahbaz, W Sligl, M Osman, DJ Kutsogiann, E MacIntyre, CR O'Neil, S Elahi Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection MBio, 2021-05-04;12(3):. 2021-05-04 [PMID: 33947753] (Human)
• R Yang, L Sun, CF Li, YH Wang, J Yao, H Li, M Yan, WC Chang, JM Hsu, JH Cha, JL Hsu, CW Chou, X Sun, Y Deng, CK Chou, D Yu, MC Hung Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy Nature Communications, 2021-02-05;12(1):832. 2021-02-05 [PMID: 33547304] (Human)
• CC Hu, WJ Jeng, YC Chen, JH Fang, CH Huang, W Teng, YC Hsieh, YC Lin, RN Chien, IS Sheen, CY Lin Memory Regulatory T cells Increase Only In Inflammatory Phase of Chronic Hepatitis B Infection and Related to Galectin-9/Tim-3 interaction Sci Rep, 2017-11-10;7(1):15280. 2017-11-10 [PMID: 29127350] (Human)
• IC Dapat, DN Pascapurna, H Iwasaki, HK Labayo, H Chagan-Yas, S Egawa, T Hattori Secretion of Galectin-9 as a DAMP during Dengue Virus Infection in THP-1 Cells Int J Mol Sci, 2017-07-28;18(8):. 2017-07-28 [PMID: 28788062] (Human)
• Gieseke F, Kruchen A, Tzaribachev N, Bentzien F, Dominici M, Muller I Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation. Eur J Immunol, 2013-07-23;43(10):2741-9. 2013-07-23 [PMID: 23817958] (Human)

FAQs for Galectin-9 (DY2045). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: LGALS9