Human Chemerin DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Chemerin DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: RARRES2

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Chemerin DuoSet ELISA, 15 Plate

• Chemerin
• RARRES2
• RAR-responsive protein TIG2
• retinoic acid receptor responder (tazarotene induced) 2
• retinoic acid receptor responder protein 2
• Tazarotene-induced gene 2 protein
• TIG-2
• TIG2HP10433

Background

Chemerin, also known as Tazarotene-induced Gene 2, (Tig-2), is a member of the Cystatin superfamily. Chemerin is synthesized as a 163 aa precursor that contains a hydrophobic 20 aa N-terminal sequence, an intervening 137 aa Cystatin fold-containing domain, and a six aa C-terminal prosegment. It is activated by proteases of the coagulation, fibrinolytic, and inflammatory cascades. Chemerin is a chemoattractant for cells bearing the Chem R23 receptor, including plasmacytoid dendritic cells and tissue macrophages.

Publications for Chemerin (DY2324)(14)

Publications using DY2324

• Höpfinger, A;Behrendt, M;Schmid, A;Karrasch, T;Schäffler, A;Berghoff, M; A Cross-Sectional Study: Systematic Quantification of Chemerin in Human Cerebrospinal Fluid Biomedicines 2024-11-01 [PMID: 39595074] (Human)
• Pavel, V;Amend, P;Schmidtner, N;Utrata, A;Birner, C;Schmid, S;Krautbauer, S;Müller, M;Mester, P;Buechler, C; Chemerin Levels in COVID-19 Are More Affected by Underlying Diseases than by the Virus Infection Itself Biomedicines 2024-09-14 [PMID: 39335612] (Human)
• Tarabeih, N;Kalinkovich, A;Ashkenazi, S;Cherny, SS;Shalata, A;Livshits, G; Relationships between Circulating Biomarkers and Body Composition Parameters in Patients with Metabolic Syndrome: A Community-Based Study International journal of molecular sciences 2024-01-10 [PMID: 38255954] (Human)
• Amend, P;Mester, P;Schmid, S;Müller, M;Buechler, C;Pavel, V; Plasma Chemerin Is Induced in Critically Ill Patients with Gram-Positive Infections Biomedicines 2023-01-01 [PMID: 37509420] (Human)
• R Jiménez-Es, D Vargas-Alc, P Flores-Esp, AC Helguera-R, O Villavicen, I Mancilla-H, C Irles, YD Torres-Ram, MY Valdespino, P Velázquez-, R Zamora-Esc, M Islas-Lópe, C Carranco-S, L Díaz, V Zaga-Clave, A Olmos-Orti High Glucose Promotes Inflammation and Weakens Placental Defenses against E. coli and S. agalactiae Infection: Protective Role of Insulin and Metformin International Journal of Molecular Sciences, 2023-03-09;24(6):. 2023-03-09 [PMID: 36982317] (Human)
• J Qi, H Sun, Y Zhang, Z Wang, Z Xun, Z Li, X Ding, R Bao, L Hong, W Jia, F Fang, H Liu, L Chen, J Zhong, D Zou, L Liu, L Han, F Ginhoux, Y Liu, Y Ye, B Su Single-cell and spatial analysis reveal interaction of FAP+ fibroblasts and SPP1+ macrophages in colorectal cancer Nature Communications, 2022-04-01;13(1):1742. 2022-04-01 [PMID: 35365629] (Human)
• R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis Biomedicines, 2022-01-07;10(1):. 2022-01-07 [PMID: 35052810] (Human)
• JHN Schuitemak, RHJ Beernink, A Franx, TIFH Cremers, MPH Koster First trimester secreted Frizzled-Related Protein 4 and other adipokine serum concentrations in women developing gestational diabetes mellitus PLoS ONE, 2020-11-18;15(11):e0242423. 2020-11-18 [PMID: 33206702] (Human)
• N Tarabeih, A Shalata, S Trofimov, A Kalinkovic, G Livshits Growth and differentiation factor 15 is a biomarker for low back pain-associated disability Cytokine, 2019-02-15;117(0):8-14. 2019-02-15 [PMID: 30776685] (Human)
• Becker M, Rabe K, Lebherz C, Zugwurst J, Goke B, Parhofer KG, Lehrke M, Broedl UC Expression of human chemerin induces insulin resistance in the skeletal muscle but does not affect weight, lipid levels, and atherosclerosis in LDL receptor knockout mice on high-fat diet. Diabetes, 2010-08-19;59(11):2898-903. 2010-08-19 [PMID: 20724582] (Human)
• Pitteri SJ, JeBailey L, Faca VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, Cheng KH, Urban N, Hanash SM, Dinulescu DM Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery. PLoS ONE, 2009-11-19;4(11):e7916. 2009-11-19 [PMID: 19936259] (Human)
• Tan BK, Chen J, Farhatullah S, Adya R, Kaur J, Heutling D, Lewandowski KC, O'Hare JP, Lehnert H, Randeva HS Insulin and metformin regulate circulating and adipose tissue chemerin. Diabetes, 2009-06-05;58(9):1971-7. 2009-06-05 [PMID: 19502420] (Human)
• Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, Fortugno P, Gonzalvo-Feo S, Franssen JD, Parmentier M, De Pita O, Girolomoni G, Sozzani S Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J. Exp. Med., 2008-12-29;206(1):249-58. 2008-12-29 [PMID: 19114666] (Human)
• Bozaoglu K, Bolton K, McMillan J, Zimmet P, Jowett J, Collier G, Walder K, Segal D Chemerin is a novel adipokine associated with obesity and metabolic syndrome. Endocrinology, 2007-07-19;148(10):4687-94. 2007-07-19 [PMID: 17640997] (Human)

FAQs for Chemerin (DY2324). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: RARRES2