Human alpha 2-Macroglobulin DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human alpha 2-Macroglobulin DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: A2M

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human alpha 2-Macroglobulin DuoSet ELISA, 15 Plate

• A2M
• alpha 2Macroglobulin
• alpha 2-Macroglobulin
• alpha-2-M
• alpha-2-macroglobulin
• C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
• CPAMD5
• CPAMD5DKFZp779B086
• FWP007
• S863-7

Background

Alpha 2-Macroglobulin (A2M) is an abundant plasma glycoprotein that has structural similarity to other A2M family members including complement components C3, C4 and C5. A2M is a tetramer (720-kDa) of 4 identical subunits (180-kDa) formed by two disulfide bond-linked dimers. It is a general and irreversible protease inhibitor capable of inhibiting all four classes of proteases by a unique trapping mechanism. A2M also binds many cytokines and growth factors. In the brain, A2M binds soluble beta Amyloid. A2M is recognized as a late onset Alzheimers disease gene.

Publications for alpha 2-Macroglobulin (DY1938)(2)

Publications using DY1938

• Lee, J;Kim, E;Park, J;Choi, S;Lee, MS;Park, J; Pre-analytical handling conditions and protein marker recovery from urine extracellular vesicles for bladder cancer diagnosis PloS one 2023-09-07 [PMID: 37676879] (Human)
• S Kuzi, M Mazaki-Tov, JS Suchodolsk, D Rimer, JA Lidbury, JM Steiner, A Buono, R Nivy, G Segev, I Aroch Protease inhibitors, inflammatory markers, and their association with outcome in dogs with naturally occurring acute pancreatitis J. Vet. Intern. Med., 2020-09-07;0(0):. 2020-09-07 [PMID: 32893923] (Canine)

Bioinformatics

• Gene Symbol: A2M