alpha 2-Macroglobulin Products

Antibodies
alpha 2-Macroglobulin Antibod ...
alpha 2-Macroglobulin Antibody [Un...
AF1938
Species: Hu
Applications: WB, Simple Western, IP, ICC/IF
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
alpha 2-Macroglobulin Antibod ...
alpha 2-Macroglobulin Antibody (25...
MAB1938
Species: Hu
Applications: WB, Simple Western
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
alpha 2-Macroglobulin Antibod ...
alpha 2-Macroglobulin Antibody
AF5798
Species: Mu
Applications: WB
Host: Sheep Polyclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human alpha 2-Macroglobulin D ...
Human alpha 2-Macroglobulin DuoSet...
DY1938
Species: Hu
Applications: ELISA
Human alpha 2-Macroglobulin E ...
Human alpha 2-Macroglobulin ELISA ...
NBP2-78771
Species: Hu
Applications: ELISA
Mouse alpha 2-Macroglobulin E ...
Mouse alpha 2-Macroglobulin ELISA ...
NBP2-60631
Species: Mu
Applications: ELISA
Lysates
alpha 2-Macroglobulin Overexp ...
alpha 2-Macroglobulin Overexpressi...
NBL1-07157
Species: Hu
Applications: WB
Proteins
Human alpha 2-Macroglobulin P ...
Human alpha 2-Macroglobulin Protei...
1938-PI
Species: Hu
Applications: Inhibition Activity
Formulation Catalog # Availability Price  
alpha 2-Macroglobulin Recombi ...
alpha 2-Macroglobulin Recombinant ...
NBP1-85491PEP
Species: Hu
Applications: AC

Description

Alpha 2 macroglobulin is a serum protein which is mainly synthesised in the liver. It functions as a broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. Alpha 2 macroglobulin is is a tetrameric molecule, and with a molecular weight of 720 kDa, it so large a molecule that it tends to remain intravascular. Following conformational change, the protinase is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites which react with receptors on a variety of cells including macrophages and liver cells. Alpha 2 macroglobulin is localized on the surface of peripheral blood lymphocytes.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2
Alternate Names
  • Alpha-2-M
  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
  • alpha-2-M
  • S863-7
  • CPAMD5DKFZp779B086
  • FWP007
  • alpha-2-macroglobulin

Research Areas for alpha 2-Macroglobulin

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Neuroscience

PTMs for alpha 2-Macroglobulin

Learn more about PTMs related to alpha 2-Macroglobulin.

Cleavage

Bioinformatics Tool for alpha 2-Macroglobulin

Discover related pathways, diseases and genes to alpha 2-Macroglobulin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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