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HAF017). A specific band was detected for a2-Macroglobulin at approximately 180 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox" target="_blank">
1938-PI) was serially diluted and captured by Mouse Anti-Human ?2‑Macroglobulin Monoclonal Antibody (Catalog # MAB19381) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human ?2‑Macroglobulin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1938) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
1938-PI) was serially diluted and captured by Mouse Anti-Human alpha 2‑Macroglobulin Monoclonal Antibody (Catalog # MAB19381) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human alpha 2‑Macroglobulin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1938) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
Alpha 2 macroglobulin is a serum protein which is mainly synthesised in the liver. It functions as a broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. Alpha 2 macroglobulin is is a tetrameric molecule, and with a molecular weight of 720 kDa, it so large a molecule that it tends to remain intravascular. Following conformational change, the protinase is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites which react with receptors on a variety of cells including macrophages and liver cells. Alpha 2 macroglobulin is localized on the surface of peripheral blood lymphocytes.
![Western Blot alpha 2-Macroglobulin Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/alpha_2Macroglobulin_AF1938_Western_Blot_20706.jpg)
![Western Blot alpha 2-Macroglobulin Antibody (257316) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/alpha_2Macroglobulin_MAB1938_Western_Blot_20710.jpg)
![N/A alpha 2-Macroglobulin [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_alpha_2Macroglobulin_DY1938_ELISA_1737.jpg)
![Simple Western alpha 2-Macroglobulin Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/alpha_2Macroglobulin_AF1938_Simple_Western_20705.jpg)
![Immunocytochemistry alpha 2-Macroglobulin Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/alpha_2Macroglobulin_AF1938_Immunocytochemistry__Immunofluorescence_17394.jpg)
![ELISA alpha 2-Macroglobulin Antibody [Unconjugated]](http://images.novusbio.com/images/af1938_human-alpha-2-macroglobulin-affinity-purified-polyclonal-ab-elisa-639201842888588162.jpg)
![ELISA alpha 2-Macroglobulin Antibody [Unconjugated]](http://images.novusbio.com/images/af1938_human-alpha-2-macroglobulin-affinity-purified-polyclonal-ab-elisa-639201850080308599.jpg)
![Simple Western alpha 2-Macroglobulin Antibody (257316) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab1938_human-alpha-2-macroglobulin-mab-clone-257316-simple-western-2362025111944..jpg)
![Simple Western alpha 2-Macroglobulin Antibody (257316) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/alpha_2Macroglobulin_MAB1938_Simple_Western_20711.jpg)
