alpha 2-Macroglobulin Products

Antibodies
alpha 2-Macroglobulin Antibod ...
alpha 2-Macroglobulin Antibody [Un...
AF1938
Species: Hu
Applications: WB, Simple Western, IP, ICC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
alpha 2-Macroglobulin Antibod ...
alpha 2-Macroglobulin Antibody (25...
MAB1938
Species: Hu
Applications: WB, Simple Western
Host: Mouse Monoclonal
alpha 2-Macroglobulin Antibod ...
alpha 2-Macroglobulin Antibody
NBP1-85491
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
alpha 2-Macroglobulin Antibod ...
alpha 2-Macroglobulin Antibody Pair
H00000002-PW1
Species: Hu
Applications: WB, IP
ELISA Kits
alpha 2-Macroglobulin ELISA K ...
alpha 2-Macroglobulin ELISA Kit [B...
KA0487
Species: Hu
alpha 2-Macroglobulin ELISA K ...
alpha 2-Macroglobulin ELISA Kit [B...
KA0486
Species: Hu
alpha 2-Macroglobulin ELISA K ...
alpha 2-Macroglobulin ELISA Kit [HRP]
KA1043
Species: Mu, Rt
Lysates
alpha 2-Macroglobulin Overexp ...
alpha 2-Macroglobulin Overexpressi...
H00000002-T01
Species: Hu
Applications: WB
alpha 2-Macroglobulin Overexp ...
alpha 2-Macroglobulin Overexpressi...
NBL1-07157
Applications: WB
Proteins
alpha 2-Macroglobulin Human E ...
alpha 2-Macroglobulin Human Expres...
NB1938-PI
Species: Hu
alpha 2-Macroglobulin Recombi ...
alpha 2-Macroglobulin Recombinant ...
NBP1-85491PEP
Species: Hu
Applications: AC
alpha 2-Macroglobulin Human E ...
alpha 2-Macroglobulin Human Expres...
P4913
Species: Hu
Applications: PAGE
RNAi
alpha 2-Macroglobulin RNAi
alpha 2-Macroglobulin RNAi
H00000002-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Alpha 2 macroglobulin is a serum protein which is mainly synthesised in the liver. It functions as a broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. Alpha 2 macroglobulin is is a tetrameric molecule, and with a molecular weight of 720 kDa, it so large a molecule that it tends to remain intravascular. Following conformational change, the protinase is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites which react with receptors on a variety of cells including macrophages and liver cells. Alpha 2 macroglobulin is localized on the surface of peripheral blood lymphocytes.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2
Alternate Names
  • Alpha-2-M
  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
  • alpha-2-M
  • S863-7
  • CPAMD5DKFZp779B086
  • FWP007
  • alpha-2-macroglobulin

Research Areas for alpha 2-Macroglobulin

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Neuroscience

PTMs for alpha 2-Macroglobulin

Learn more about PTMs related to alpha 2-Macroglobulin.

Cleavage

Bioinformatics Tool for alpha 2-Macroglobulin

Discover related pathways, diseases and genes to alpha 2-Macroglobulin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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