HSD11B2 Antibody

Western Blot: HSD11B2 Antibody [NBP1-53163] - Human Muscle lysate, concentration 0.2-1 ug/ml.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

HSD11B2 Antibody Summary

• Immunogen: Synthetic peptides corresponding to HSD11B2(hydroxysteroid (11-beta) dehydrogenase 2) The peptide sequence was selected from the N terminal of HSD11B2. Peptide sequence ERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRL. The peptide sequence for this immunogen was taken from within the described region.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HSD11B2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1.0 ug/ml
• Application Notes: This is a rabbit polyclonal antibody against HSD11B2 and was validated on Western blot.
• Theoretical MW: 45 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS & 2% Sucrose.
• Preservative: 0.09% Sodium Azide
• Purity: Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for HSD11B2 Antibody

• 11 betaHSD2
• 11 beta-HSD2
• AME
• corticosteroid 11-beta-dehydrogenase isozyme 2,11-beta-HSD2
• EC 1.1.1
• EC 1.1.1.-
• HSD11B2
• HSD11KAME1
• HSD2,11-DH2
• hydroxysteroid (11-beta) dehydrogenase 2
• NAD-dependent 11-beta-hydroxysteroid dehydrogenase
• SDR9C3
• short chain dehydrogenase/reductase family 9C member 3,11-beta-hydroxysteroid dehydrogenase type 2

Background

HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HSD11B2
• Uniprot:
  • P80365()