HSD11B2 Products

Antibodies
HSD11B2 Antibody (921215) [Un ...
HSD11B2 Antibody (921215) [Unconju...
MAB8630
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
HSD11B2 Antibody
HSD11B2 Antibody
NBP2-37954
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HSD11B2 Antibody
HSD11B2 Antibody
NBP2-37898
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
HSD11B2 Overexpression Lysate ...
HSD11B2 Overexpression Lysate (Nat...
NBL1-11721
Applications: WB
HSD11B2 Overexpression Lysate ...
HSD11B2 Overexpression Lysate (Den...
H00003291-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human HSD11B2 Pro ...
Recombinant Human HSD11B2 Protein
H00003291-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human HSD11B2 Pro ...
Recombinant Human HSD11B2 Protein
H00003291-Q01
Species: Hu
Applications: WB, ELISA, PA
HSD11B2 Recombinant Protein A ...
HSD11B2 Recombinant Protein Antigen
NBP2-37954PEP
Species: Hu
Applications: AC

Description

HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. The protein modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. Defects in HSD11B2 are the cause of apparent mineralocorticoid excess (AME). AME is a potentially fatal disease characterized by severe juvenile low-renin hypertension, sodium retention, hypokalemia and low levels of aldosterone. It often leads to nephrocalcinosis.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 3291
Alternate Names
  • EC 1.1.1
  • NAD-dependent 11-beta-hydroxysteroid dehydrogenase
  • EC 1.1.1.-
  • short chain dehydrogenase/reductase family 9C member 3,11-beta-hydroxysteroid dehydrogenase type 2
  • corticosteroid 11-beta-dehydrogenase isozyme 2,11-beta-HSD2
  • HSD2,11-DH2
  • SDR9C3
  • HSD11KAME1
  • AME
  • hydroxysteroid (11-beta) dehydrogenase 2

Research Areas for HSD11B2

Find related products by research area and learn more about each of the different research areas below.

Stem Cell Markers

PTMs for HSD11B2

Learn more about PTMs related to HSD11B2.

Methylation
Cleavage
Oxidation
Demethylation
Phosphorylation
Deacetylation
Acetylation

Bioinformatics Tool for HSD11B2

Discover related pathways, diseases and genes to HSD11B2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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