HO-1/HMOX1/HSP32 ELISA Development Kit

ELISA: HO-1/HMOX1/HSP32 ELISA Kit (Colorimetric) [NBP2-61292] - These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Product Discontinued

HO-1/HMOX1/HSP32 ELISA Development Kit Summary

• Description: HO-1 ELISA development set contains sufficient reagents for the development of 5 x 96 well ELISA plates which provides analysis of ~200 samples in duplicate
• Standard Curve Range: 0.195 - 12.5 ng/ml
• Sensitivity: 39 pg/ml
• Sample Volume: 100 uL
• Kit Type: ELISA Development Kit
• Gene: HMOX1

Packaging, Storage & Formulations

• Storage: Store at 4°C.

Alternate Names for HO-1/HMOX1/HSP32 ELISA Development Kit

• bK286B10
• EC 1.14.99.3
• heat shock protein, 32-kD
• heme oxygenase (decycling) 1
• HMOX1
• HO
• HO1
• HO-1
• HO-1heme oxygenase 1
• HSP32

Background

Stressed mammalian cells up-regulate heme oxygenase 1 (HO-1), which catabolizes heme to biliverdin, carbon monoxide, and free iron. Results provide genetic evidence that up-regulation of HO-1 serves as an adaptive mechanism to protect cells from oxidative damage during stress (1). When cells are injured they release their contents, resulting in a local accumulation of free heme proteins and heme. HO-1 plays a crucial role in the inflammatory process during wound healing (2). TNFalpha accelerates inflammatory responses by down-regulating HO-1 expression in human monocytes. TNF antagonists may block this TNF-dependent suppression of HO-1 expression, resulting in an amelioration of inflammation (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: HMOX1