HMGCS2 Antibody - Azide and BSA Free

Western Blot: HMGCS2 Antibody [H00003158-D01P] - Analysis of HMGCS2 expression in transfected 293T cell line by HMGCS2 polyclonal antibody.Lane 1: HMGCS2 transfected lysate(56.60 KDa).Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

HMGCS2 Antibody - Azide and BSA Free Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: HMGCS2 (NP_005509.1, 1 a.a. - 508 a.a.) full-length human protein. MQRLLTPVKRILQLTRAVQETSLTPARLLPVAHQRFSTASAVPLAKTDTWPKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFYHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRPV
• Specificity: Reacts with 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HMGCS2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HMGCS2 Antibody - Azide and BSA Free

• 3-hydroxy-3-methylglutaryl coenzyme A synthase
• 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
• 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)
• EC 2.3.3.10
• HMG-CoA synthase
• hydroxymethylglutaryl-CoA synthase, mitochondrial
• mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase

Background

Mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase (HMGCS2; EC 2.3.3.10) mediates the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for brain, heart, kidney, and other organs during times of carbohydrate deprivation such as fasting (Robinson and Williamson, 1980 [PubMed 6986618]). Also see cytoplasmic HMG-CoA synthase (HMGCS1; MIM 142940), which mediates an early step in cholesterol synthesis.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HMGCS2
• Entrez:
  • 3158(Human)
• Uniprot:
  • NP_005509.1(Human)