Western Blot: Histone H3 [ac Lys9, ac Lys14] Antibody [NB21-1081] - WB analysis of H3K9ac/K14ac in C. elegans embryo lysate.
Immunocytochemistry: Histone H3 [ac Lys9, ac Lys14] Antibody [NB21-1081] - Immunofluorescence: [NB21-1081] - Histone H3.2 K9,K14ac antibody was tested at 1:50 in HeLa cells with FITC. Nuclei and actin were ...read more
Flow Cytometry: Histone H3 [ac Lys9, ac Lys14] Antibody [NB21-1081] - Analysis of Alexa Fluor (R) 700 conjugate of NB21-1081. Jurkat cells stained with Alexa Fluor 700 conjugated acetylated Histone H3 antibody (blue) or ...read more
Western Blot: Histone H3 [ac Lys9, ac Lys14] Antibody [NB21-1081] - WB analysis of H3 K9ac/K14ac in NIH/3T3 histone preps.
Dot Blot: Histone H3 [ac Lys9, ac Lys14] Antibody [NB21-1081] - Dot blot analysis of H3 K36ac in picomoles of peptide.
Human, mouse, and C. elegans. Predicted to react with many species including rat, chicken, Xenopus, Drosophila, and plant based on 100% sequence homology.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS and 30% Glycerol
0.05% Sodium Azide
Immunogen affinity purified
Epi-Plus antibody production in collaboration with Rockland Immunochemicals Inc.
Alternate Names for Histone H3 [ac Lys9, ac Lys14] Antibody
H3 histone, family 3A
Acetylation at K9 and K14 of histone H3 is known to be an epigenetic modification associated with active transcription. Under cellular stress conditions, H3K9ac/K14ac levels increase, probably due to the inactivation of the HDA6 histone deacetylase. Particularly, during infections with herpes simplex virus, the acute phase of the infection is demarcated by increased presence of H3K9ac/K14ac associated with transcriptionally active euchromatin. The virus seems to take advantage of the highly transcribed regions of euchromatin for viral replication, increasing the lytic infection.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
The role of DNMT3A in development Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence. Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation. Gene silencing in DNA ... Read full blog post.
Histone H3 Eukaryotic chromosomes are formed through the highly organized and structural wrapping of DNA genetic material around histone proteins into the classic "bead on a string" globular structure of nucleosomes. The histone family consists of five family me... Read full blog post.
EZH2: Epigenetic Regulation Made Easy! Enhancer of Zeste homolog 2 (EZH2) is the methyltransferase enzyme responsible for trimethylating lysine 27 on histone H3 to produce H3K27Me3. EZH2 is a polycomb group protein that is an essential epigenetic regulator that is often found deregulated i... Read full blog post.
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