Histone H3 Products

Antibodies
Histone H3 Antibody
Histone H3 Antibody
Species: Hu, Mu, Rt, Xp, Ye, C. elegans, Chicken, Drosophila, Plant
Applications: WB, ChIP, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
Histone H3 [Trimethyl Lys4] A ...
Histone H3 [Trimethyl Lys4] Antibody
Species: Hu, Mu, Ce, Chicken, Drosophila, Plant, Rat, Xenopus
Applications: WB, ChIP, DB, ICC/IF
Host: Rabbit Polyclonal
Kits
Histone H3 Assay Kit
Histone H3 Assay Kit
NBP1-94204
Histone H3 ChIP Kit
Histone H3 ChIP Kit
KA0698
Applications: ChIP
Histone H3 ChIP Kit
Histone H3 ChIP Kit
KA0700
Applications: ChIP
Lysates
Histone H3 Overexpression Lys ...
Histone H3 Overexpression Lysate (...
NBP2-06577
Applications: WB
Proteins
Histone H3 [p Thr11] Peptide
Histone H3 [p Thr11] Peptide
NB21-1101PEP
Species: Hu
Histone H3 [p Thr6] Peptide
Histone H3 [p Thr6] Peptide
NB21-1051PEP
Species: Hu
Histone H3 [Monomethyl Lys18] ...
Histone H3 [Monomethyl Lys18] Peptide
NB21-1141PEP
Species: Hu
RNAi
Histone H3 RNAi
Histone H3 RNAi
H00126961-R01
Species: Hu
Histone H3 RNAi
Histone H3 RNAi
H00008350-R01
Species: Hu

Description

Histone H3 is 136 amino acids long, weighs approximately 15 kDa, and is part of a group of basic nuclear proteins called histones, which are responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Current studies are being done on several diseases and disorders including x inactivation, systemic lupus erythematosus, lupus erythematosus, immunodeficiency, leukemia, and retinoblastoma. Histone H3 has also been shown to have interactions with HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, and HIST1H4F in pathways such as the developmental notch signaling, histone modification, chromosome condensation, interferon, hemostasis, meiosis, and meiotic recombination pathways.

Bioinformatics

Entrez Human
Human
Human
Human
Human
Human
Human
Mouse
Mouse
Mouse
Rat
Rat
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Mouse
Mouse
Product By Gene ID 126961
Alternate Names
  • H3.3B
  • MGC87782
  • histone H3.3
  • H3.3AH3F3H3F3B
  • MGC87783
  • H3 histone, family 3A

Research Areas for Histone H3

Find related products by research area and learn more about each of the different research areas below.

Chromatin Modifiers
Chromatin Research
Epigenetics
Histones and Modified Histones
Phospho-Specific

Bioinformatics Tool for Histone H3

Discover related pathways, diseases and genes to Histone H3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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Related Histone H3 Blog Posts

Check out the latest blog posts on Histone H3.
The role of DNMT3B in the co-incidence of methyltransferase and tumor suppressor expression in malignancies
Epigenetics is the process of heritable change in gene activity despite alteration of the hosts DNA sequence, essentially causing a change in a phenotype without a change in the genotype of a host. To change the gene sequence without interfering w...    Read more.
The role of DNMT3A in development
Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...    Read more.
EZH1 has more to offer than gene repression
EZH1 is part of the Polycomb-group family of proteins, which are responsible for remodeling chromatin in genes and modulating epigenetic silencing during development.  Specifically, EZHI is a component of PRC2, or polycomb repressive complex-2.  PR...    Read more.
Understanding Transcription with RNA Polymerase II
RNA polymerase II is a large 12-subunit complex that synthesizes all mRNAs and several non-coding RNAs in eukaryotic cells. It is a DNA-dependent RNA polymerase enzyme that catalyzes transcription of DNA into RNA based on the four ribonucleoside triph...    Read more.
Histone H3
Eukaryotic chromosomes are formed through the highly organized and structural wrapping of DNA genetic material around histone proteins into the classic "bead on a string" globular structure of nucleosomes. The histone family consists of five family me...    Read more.
EZH2: Epigenetic Regulation Made Easy!
Enhancer of Zeste homolog 2 (EZH2) is the methyltransferase enzyme responsible for trimethylating lysine 27 on histone H3 to produce H3K27Me3. EZH2 is a polycomb group protein that is an essential epigenetic regulator that is often found deregulated i...    Read more.
Understanding the Reasons for Histone H3 K4 Trimethylation (H3K4Me3)
Epigenetic mechanisms allow distinction between the active and inactive compartments of the genome, allowing proper cell lineage and embryogenesis. The trimethylation of Histone 3 at lysine 4 (H3K4Me3) is a common epigenetic histone modification that...    Read more.
The 'epi-genie' is Out of the Bottle: Functional Histone 3 Variants in Human Disease
Discovery of histone variants using highly specific antibodies has led to the emerging notion that alterations in histone modifications and further changes in chromatin structure are induced by exchange of histone variants. Covalent histone modificati...    Read more.
"Come Fly with Me" - New Drosophila Model Developed for Direct in Vivo Study of Histones
Forming the major protein component of chromatin, histones are essential to the structure and organization of chromosomes, forming the nucleosome around which DNA is packaged and wrapped.Antibody studies have revealed histones undergo various posttr...    Read more.
Read more Histone H3 related blogs.