Histone H2a Products

Description

Changes in chromatin structure play a large role in the regulation of transcription in eukaryotes (1). The nucleosome is the primary building block of chromatin, and is made up of four core histone proteins (H2A, H2B, H3 and H4) (2). It has been shown that DNA damage induces monoubiquitylation of histone H2A in the vicinity of DNA lesions. Ultraviolet -induced monoubiquitylation of H2A is dependent on functional nucleotide excision repair. It occurs after incision of the damaged strand and forms part of the cellular response to UV damage and suggests a role of this modification in DNA repair-induced chromatin remodeling (3).

Bioinformatics

Entrez	8338 Human 92815 Human 221613 Human 24828 Rat
Uniprot	P0C0S8 Human Q96QV6 Human NP_003508.1 Human Q16777 Human
Product By Gene ID	8338
Alternate Names	histone IIa Histone H2A-GL101 histone H2A type 2-C histone 2, H2ac MGC74460 H2A histone family, member Q H2A-GL101 H2A/q H2AFQH2A Histone H2A/q histone cluster 2, H2ac

Research Areas for Histone H2a

Find related products by research area and learn more about each of the different research areas below.

Chromatin Research
Epigenetics
Histones and Modified Histones

Bioinformatics Tool for Histone H2a

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